Evidence map›Paper›PMID 41993136›Full record

ArticleFrontiers in transplantation2026

Exploratory biomarkers for acute rejection in vascularized composite allotransplantation.

Dominika Pullmann, William J Rifkin, Haruyuki Hirayama, Bruce E Gelb, Ata S Moshiri, Massimo Mangiola, Eduardo D Rodriguez, Catherine P Lu, Piul S Rabbani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dominika Pullmann *Hansjörg Wyss Department of Plastic Surgery, New York University School of Medicine, New York, NY, United States.
William J Rifkin *Hansjörg Wyss Department of Plastic Surgery, New York University School of Medicine, New York, NY, United States.
Haruyuki Hirayama *Hansjörg Wyss Department of Plastic Surgery, New York University School of Medicine, New York, NY, United States.
Bruce E GelbTransplant Institute, New York University School of Medicine, New York, NY, United States.
Ata S MoshiriRonald O. Perelman Department of Dermatology, New York University School of Medicine, New York, NY, United States.
Massimo MangiolaDepartment of Cell Biology and Regenerative Medicine Institute, New York University School of Medicine, New York, NY, United States.
Eduardo D RodriguezHansjörg Wyss Department of Plastic Surgery, New York University School of Medicine, New York, NY, United States.
Catherine P LuHansjörg Wyss Department of Plastic Surgery, New York University School of Medicine, New York, NY, United States.
Piul S RabbaniHansjörg Wyss Department of Plastic Surgery, New York University School of Medicine, New York, NY, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascularized composite allotransplantation (VCA) involves immunologically heterogeneous tissues with a high incidence of acute rejection. Reliable and timely detection of rejection onset remains a major unmet challenge in VCA management. This longitudinal exploratory case study assessed blood- and tissue-derived biomarkers for acute rejection monitoring in a full-face and bilateral hand transplant recipient over 4.6 years. Of these biomarkers, donor-derived cell-free DNA (dd-cfDNA) and short tandem repeats (STR) showed trends toward elevated recipient levels during acute rejection, though differences were not statistically significant. CD8

Indexed as

biomarkersreconstructive transplantationreconstructive transplant surgeryrejection biomarkersrejection monitoringvascularized composite allotransplantation (VCA)

Identifiers

PMID41993136
PMCPMC13079665

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.