Evidence map›Paper›PMID 41993072›Full record

ArticleInternational journal of pharmaceutics: X2026

Hybrid membrane-camouflaged photothermal immunomodulatory nanoparticle inhibits colorectal cancer growth and metastasis.

Yuan Zhu, Yishu Lin, Tao Wang, Wanyi Liu, Qi Xia, Yuanye Jiang, Yan Zhao, Hongtao Wang, Chuanhe Xia, Jiafeng Zou and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of pharmaceutics: X, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yuan ZhuCentral Laboratory, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Yishu LinCentral Laboratory, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Tao WangCentral Laboratory, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Wanyi LiuCentral Laboratory, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Qi XiaCentral Laboratory, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Yuanye JiangDepartment of Gastroenterology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Yan ZhaoNursing Department, Shanghai Putuo District Changzheng Town Community Health Service Center, Shanghai 200062, China.
Hongtao WangShanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China.
Chuanhe XiaShanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China.
Jiafeng ZouShanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China.
Peihao YinCentral Laboratory, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Feng GaoShanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China.
Zeting YuanCentral Laboratory, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photothermal therapy (PTT) alone is insufficient for the complete elimination of malignant cells, which may lead to recurrence and metastasis. Thus, PTT is usually used in combination with immunomodulatory therapy. Herein, hybrid cell membrane biomimetic nanoparticle was developed by fusing a Raw 264.7 macrophage-derived extracellular vesicle membrane (Rm) and a CT26 cell membrane (Cm) to encapsulate imiquimod ( Chemical compounds studied in this article: Imiquimod (R837, PubChem CID: 57469), Polydopamine (PDA), Iron (II,III) oxide (Fe₃O₄, PubChem CID: 16211978), Coumarin 6 (C6, PubChem CID: 100334), IR775 chloride (PubChem CID: 44465046).

Indexed as

Cell membrane biomimetic nanoparticleColorectal cancerImiquimodImmunogenic cell deathPhotothermal therapy

Identifiers

PMID41993072
PMCPMC13081185

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.