Evidence map›Paper›PMID 41993036›Full record

ReviewCell cycle (Georgetown, Tex.)2026

Functional relevance of piRNA-PIWI axis in cancers: diagnostic and therapeutic avenues.

Narendra Kumar Sharma, Sonam Chawla, Nitya Tiwari, Kavita R, Shefali Gulliya, Pawan Kumar Maurya, Tikam Chand Dakal

Abstract readReview
In one paragraph

Review in Cell cycle (Georgetown, Tex.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Narendra Kumar SharmaDepartment of Bioscience and Biotechnology, Banasthali Vidyapith, Niwai, India.ORCID 0000-0002-8681-3840
Sonam ChawlaDepartment of Biotechnology, Jaypee Institute of Information Technology, Noida, India.ORCID 0000-0002-6187-4778
Nitya TiwariDepartment of Bioscience and Biotechnology, Banasthali Vidyapith, Niwai, India.ORCID 0009-0004-5081-3592
Kavita RDepartment of Bioscience and Biotechnology, Banasthali Vidyapith, Niwai, India.
Shefali GulliyaDepartment of Bioscience and Biotechnology, Banasthali Vidyapith, Niwai, India.ORCID 0000-0002-6240-3644
Pawan Kumar MauryaDepartment of Biochemistry, Central University of Haryana, Mahendergarh, India.
Tikam Chand DakalGenome and Computational Biology Lab, Department of Biotechnology, Mohanlal Sukhadia University, Udaipur, India.ORCID 0000-0002-9248-7391

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Piwi-interacting RNAs (piRNAs) and PIWI proteins are emerging key players in the regulation of cancer gene expression and tumor biology. piRNAs (24-31 nucleotides), interact with PIWI proteins to regulate gene expression

Indexed as

Argonaute ProteinsNeoplasmsPiwi-Interacting RNARNA, Small InterferingAnimalsGene Expression Regulation, NeoplasticHumansArgonaute ProteinsPiwi-Interacting RNARNA, Small Interferingcancer biomarkersliquid biopsyonco-therapypiRNAPIWI proteins

Identifiers

PMID41993036
PMCPMC13094221

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.