Evidence map›Paper›PMID 41992697›Full record

ArticleEpidemiology and infection2026

Congenital syphilis in Portugal, 2015-2024: Temporal-spatial characterization and gaps in prevention of vertical transmission.

Filipa Canha, Sebastian von Schreeb, Pedro Parreira da Silva, Inês Martins, Ana Mendes, Dina Oliveira, Pedro Pinto Leite, Vítor Cabral Veríssimo

Abstract read
In one paragraph

Article in Epidemiology and infection, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Filipa CanhaPublic Health Service, https://ror.org/03j4tqp21Almada-Seixal Local Health Unit, Portugal.ORCID https://orcid.org/0000-0003-3336-8306
Sebastian von SchreebCenter for Public Health Emergencies, https://ror.org/04k7qar56Directorate-General of Health, Portugal.ORCID https://orcid.org/0000-0002-1442-2621
Pedro Parreira da SilvaUnidade de Saúde Familiar do Parque, Santa Maria Local Health Unit, Portugal.
Inês MartinsDepartment of Obstetrics and Gynecology, Santa Maria University Hospital, Local Health Unit of Santa Maria, Lisbon, Portugal.
Ana MendesDirectorate of Information and Analysis, https://ror.org/04k7qar56Directorate-General of Health, Portugal.
Dina OliveiraDirectorate of Disease Prevention and Health Promotion, https://ror.org/04k7qar56Directorate-General of Health, Portugal.
Pedro Pinto LeiteDirectorate of Information and Analysis, https://ror.org/04k7qar56Directorate-General of Health, Portugal.
Vítor Cabral VeríssimoDirectorate of Information and Analysis, https://ror.org/04k7qar56Directorate-General of Health, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aligned with the increasing trend observed across the EU/EEA, congenital syphilis (CS) cases have risen in Portugal, which has the third highest rate per 100000 live births in the EU/EEA. This study aimed to analyse CS cases reported in Portugal, focusing on pregnancy monitoring and antenatal screening to identify gaps in preventing vertical transmission of syphilis. We conducted a descriptive study, including confirmed CS cases reported in Portugal from 2015 to 2024. We calculated annual incidence per 100000 live births and the proportion of pregnancies monitored and antenatal screenings performed. During 2015-2024, 99 confirmed CS cases were reported, 64.6% in infants under 1 month of age. The incidence of CS increased eightfold from 2016 to 2024. Among mothers of CS cases, 67.7% had pregnancies classified as monitored; of these, 77.6% had a record of antenatal screening, and 88.5% of those screened tested positive. These findings highlight potential fragilities in antenatal care, diagnosis and treatment, contributing to the resurgence of CS in Portugal. Addressing missed opportunities for prevention requires improving maternal healthcare, strengthening surveillance systems, and ensuring the timely treatment of pregnant people and their partners, in order to reverse this trend and move towards the elimination of vertical transmission of syphilis.

Indexed as

Infectious Disease Transmission, VerticalPregnancy Complications, InfectiousSyphilis, CongenitalAdultFemaleHumansIncidenceInfantInfant, NewbornPortugalPregnancyPrenatal DiagnosisSpatio-Temporal AnalysisYoung Adultantenatal carecongenital syphiliseliminationpreventionsurveillancevertical transmission

Identifiers

PMID41992697
PMCPMC13366361

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.