ArticlePest management science2026
Design, synthesis, and antifungal activity of anethole-based oxime ester compounds as potential laccase inhibitors.
Article in Pest management science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe improper application of traditional fungicides frequently results in issues such as low fungicide utilization efficiency and environmental contamination. The advent of nanopesticides derived from natural products provides a more promising solution for the green management of agricultural diseases.
resultsIn this study, laccase was selected as the biological target, and 24 novel anethole-based oxime ester compounds were rationally designed and synthesized. The chemical structures of these target compounds were systematically validated using Fourier-transform infrared spectroscopy (FT-IR), proton nuclear magnetic resonance (
conclusionThe target compound 4w may exert potent antifungal activity via laccase inhibition, thereby holding significant potential as a lead compound for the development of the novel green fungicide. Concurrently, the 4w/AMCS-3 complex exhibited promise as a nanopesticide candidate, warranting further investigation. © 2026 Society of Chemical Industry.
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