Evidence map›Paper›PMID 41992522›Full record

ReviewJournal of cosmetic dermatology2026

A Psychological Guide to Lower Face Botulinum Toxin Injections: Baseline Emotional Functions of Facial Expressions.

Alexander G M Hopf, Anna Buchheim, Marietta Hopf, Dirk W Eilert

Abstract readReview
In one paragraph

Review in Journal of cosmetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alexander G M HopfInstitute of Psychology, University of Innsbruck, Innsbruck, Austria.ORCID https://orcid.org/0009-0003-5174-8502
Anna BuchheimInstitute of Psychology, University of Innsbruck, Innsbruck, Austria.ORCID https://orcid.org/0000-0002-1339-5246
Marietta HopfVilla Dahlem, Private Practice, Berlin, Germany.
Dirk W EilertInstitute of Psychology, University of Innsbruck, Innsbruck, Austria.ORCID https://orcid.org/0009-0000-2708-9605

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe lower face conveys critical interpersonal signals and is central to how patients are emotionally evaluated by others. As botulinum toxin type A (BoNT-A) is increasingly used in the perioral and mandibular region, there is a growing need to understand how such procedures may influence both aesthetic outcomes and the dynamics of emotional communication and social perception.

aimsThis narrative review outlines the baseline emotional functions of lower-face expressions and supports clinicians in integrating emotional and interpersonal considerations into BoNT-A treatment planning.

methodsA narrative literature review was conducted using PubMed and Scopus, combining the search terms 'botulinum toxin', 'lower face', 'facial expression', 'emotion', 'mimicry', and 'psychology'. Relevant evidence from psychology and neuroscience was synthesized to identify emotional and social signaling functions of key lower-face Action Units (AUs). Additional insights were integrated through citation tracking and clinical experience.

resultsLower-face BoNT-A targets, such as the depressor anguli oris, platysma, masseter, mentalis, and orbicularis oris, are part of distinct AUs that contribute to emotion expression and interpersonal signaling. Their modulation through BoNT-A potentially alters cues linked to socially relevant emotions such as sadness and contempt, and social dimensions, including dominance and approachability, thereby affecting how patients are perceived in social contexts.

conclusionsUnderstanding the psychological and communicative functions of the lower face helps anticipate how BoNT-A treatments may influence emotional signaling and social perception. Incorporating these insights into aesthetic consultations supports transparent counseling and strengthens awareness of how aesthetic interventions contribute to nonverbal communication.

Indexed as

Botulinum Toxins, Type ACosmetic TechniquesEmotionsFacial ExpressionFacial MusclesNeuromuscular AgentsEstheticsHumansSocial PerceptionBotulinum Toxins, Type ANeuromuscular Agentsbotulinum toxinexpressive flexibilityfacial emotionsfacial expressionsfacial feedbackresting bitch face

Identifiers

PMID41992522
PMCPMC13087203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.