Evidence map›Paper›PMID 41992498›Full record

ArticleActa obstetricia et gynecologica Scandinavica2026

Step-by-step combined surgical approach to successfully repair complex and challenging vesico-vaginal fistulas: Insights from a case series.

Martina Arcieri, Stefano Restaino, Veronica Tius, Andrea Lombisani, Davide Arrigo, Lavinia Porto, Giovanni Panico, Daniela Caramazza, Lorenzo Vacca, Giuseppe Campagna and 3 more

Abstract read
In one paragraph

Article in Acta obstetricia et gynecologica Scandinavica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Martina ArcieriClinic of Obstetrics and Gynecology, "Santa Maria della Misericordia" University Hospital, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy.ORCID 0000-0002-8257-0618
Stefano RestainoClinic of Obstetrics and Gynecology, "Santa Maria della Misericordia" University Hospital, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy.ORCID 0000-0002-7848-0329
Veronica TiusMedical Area Department (DAME), in Department of Medicine (DMED), University of Udine, Udine, Italy.ORCID 0009-0008-6178-2233
Andrea LombisaniPrecision Gynaecological Surgery Unit, Dipartimento Centro di Eccellenza Donna e Bambino Nascente, Fatebenefratelli Gemelli Isola Tiberina, Rome, Italy.
Davide ArrigoDepartment of Woman, Child and Public Health, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.ORCID 0009-0006-1911-1060
Lavinia PortoDepartment of Human Pathology of Adult and Childhood "Gaetano Barresi", Unit of Obstetrics and Gynecology, University of Messina, Messina, Italy.
Giovanni PanicoDepartment of Woman, Child and Public Health, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.ORCID 0000-0001-5473-9503
Daniela CaramazzaPrecision Gynaecological Surgery Unit, Dipartimento Centro di Eccellenza Donna e Bambino Nascente, Fatebenefratelli Gemelli Isola Tiberina, Rome, Italy.ORCID 0000-0003-0858-025X
Lorenzo VaccaPrecision Gynaecological Surgery Unit, Dipartimento Centro di Eccellenza Donna e Bambino Nascente, Fatebenefratelli Gemelli Isola Tiberina, Rome, Italy.ORCID 0000-0003-3774-0259
Giuseppe CampagnaPrecision Gynaecological Surgery Unit, Dipartimento Centro di Eccellenza Donna e Bambino Nascente, Fatebenefratelli Gemelli Isola Tiberina, Rome, Italy.ORCID 0000-0003-2128-077X
Canio MartinelliDepartment of Human Pathology of Adult and Childhood "Gaetano Barresi", Unit of Obstetrics and Gynecology, University of Messina, Messina, Italy.ORCID 0000-0002-0587-8467
Giuseppe VizzielliClinic of Obstetrics and Gynecology, "Santa Maria della Misericordia" University Hospital, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy.ORCID 0000-0002-2424-2691
Alfredo ErcoliDepartment of Human Pathology of Adult and Childhood "Gaetano Barresi", Unit of Obstetrics and Gynecology, University of Messina, Messina, Italy.ORCID 0000-0002-5019-5526

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSeveral surgical approaches are available for the repair of complex vesico-vaginal fistulas; however, robust clinical evidence and standardization of techniques are lacking. Complex vesico-vaginal fistula is defined as either a recurrent fistula following primary surgical repair or a fistula related to prior pelvic surgery and/or radiotherapy. The aim of this study was to describe a step-by-step combined vaginal and laparoscopic technique and to assess its feasibility, safety, and efficacy. MATERIAL AND

methodsA retrospective study was performed between 2016 and 2023, involving patients diagnosed with complex vesico-vaginal fistulas. Clinical, perioperative, and postoperative data were collected. The surgical technique was standardized, described, and executed by an experienced surgeon in each case. Postoperative urogynecological follow-up was scheduled at one month, 3 months, 6 months, and one year.

resultsA total of 20 patients were included in the study. Fifteen patients developed vesico-vaginal fistulas after total hysterectomy, four after radical hysterectomy combined with radiotherapy, and one following a cesarean section. Four patients had a prior diagnosis of gynecological cancer, four had received pelvic radiotherapy, and two had undergone previous chemotherapy. Twenty-five percent of the patients exhibited VVF in the trigone area. The median operative time was 317 min (ranging from 250 to 508 min). One minor postoperative complication occurred, and there was no conversion to laparotomy. All repairs were watertight. The median length of hospital stay was 4 days (ranging from 2 to 6 days). No recurrences were observed during the follow-up period, lasting 42 months on average.

conclusionsThis study demonstrated the feasibility and safety of a new surgical approach for repairing complex urogenital fistulas.

Indexed as

Gynecologic Surgical ProceduresLaparoscopyVesicovaginal FistulaAdultAgedFeasibility StudiesFemaleHumansMiddle AgedPostoperative ComplicationsRetrospective StudiesTreatment Outcomelaparoscopyminimally invasive surgeryvaginal surgeryvesico‐vaginal fistula

Identifiers

PMID41992498
PMCPMC13191793

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.