ArticlePest management science2026
Integrative screening of plant volatiles through transient receptor potential channel docking, olfactometry, and field validation in Bemisia tabaci.
Article in Pest management science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundBemisia tabaci is a globally damaging pest for which insecticide reliance and resistance demand eco-rational, mechanism-informed alternatives. This study aimed to build a multi-tier pipeline of (TRP) channel docking, Y-tube olfactometry, RNA interference (RNAi) functional validation, and field trapping to identify and mechanistically support plant volatile attractants for improved monitoring/management.
resultsDocking of 51 volatile organic compounds against six modelled TRP receptors (Transient Receptor Potential Cation Channel Subfamily A Member 1 (TRPA1), TRPV-Inactive, TRPL, Transient Receptor Potential Melastatin (TRPM), TRPML, TRPP-PKD1) yielded binding energies from -3.2 to -7.6 kcal mol
conclusionThe convergence of docking affinity, lab attraction, RNAi-dependent behavioural suppression, and consistent field performance supports TRPA1/TRPM as key contributors to volatile-guided orientation and delivers validated attractants (notably thymol, β-caryophyllene, cuminaldehyde) for stronger, more reliable whitefly monitoring and semiochemical-based integrated pest management. © 2026 Society of Chemical Industry.
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