Evidence map›Paper›PMID 41992299›Full record

ArticleJournal of nanobiotechnology2026

Multi-enzymatic catalysis copper ceria-polyphenol nanozyme for balancing peroxidase catalysis and reactive oxygen scavenging: a synergistic strategy for enhancing drug-resistant bacteria eradication.

Caizhen Liang, Yingsi Wang, Yanling Xu, Gang Zhou, Qingshan Shi, Xiaobao Xie

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Caizhen LiangGuangdong Provincial Key Laboratory of Microbial Culture Collection and Application, State Key Laboratory of Applied Microbiology Southern China, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, 510070, People's Republic of China.
Yingsi WangGuangdong Provincial Key Laboratory of Microbial Culture Collection and Application, State Key Laboratory of Applied Microbiology Southern China, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, 510070, People's Republic of China.
Yanling XuGuangdong Provincial Key Laboratory of Microbial Culture Collection and Application, State Key Laboratory of Applied Microbiology Southern China, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, 510070, People's Republic of China.
Gang ZhouGuangdong Provincial Key Laboratory of Microbial Culture Collection and Application, State Key Laboratory of Applied Microbiology Southern China, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, 510070, People's Republic of China.
Qingshan ShiGuangdong Provincial Key Laboratory of Microbial Culture Collection and Application, State Key Laboratory of Applied Microbiology Southern China, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, 510070, People's Republic of China. shiqingshan@hotmail.com.
Xiaobao XieGuangdong Provincial Key Laboratory of Microbial Culture Collection and Application, State Key Laboratory of Applied Microbiology Southern China, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, 510070, People's Republic of China. xiexb@gdim.cn.

Funding

National Natural Science Foundation of China 52501312
6 · The paper itself

Abstract

Strong catalysis and novel copper-induced cell death enable copper-based nanozymes to present good bactericidal capacity against antibiotic-resistant pathogens, but their aspect of the balance between low ROS and low-dose antibacterial performance remains a significant challenge. Herein, an innovative copper/cerium (Cu/Ce)-doped metal-polyphenol network nanozyme (CCP) was synthesized for synergistically modulating the multi-enzymatic activities and enhancing methicillin-resistant Staphylococcus aureus (MRSA) eradication, where Cu and Ce individually decorated on carbon nanosheet skeleton. Benefited from the Cu/Ce dual-site structure, CCP exhibited remarkable multi-enzymatic (superoxide dismutase-, peroxidase-, glutathione peroxidase-, and nicotinamide adenine dinucleotide peroxidase-like) and

Indexed as

Anti-Bacterial AgentsCeriumCopperMethicillin-Resistant Staphylococcus aureusReactive Oxygen SpeciesBiofilmsCatalysisHydrogen PeroxideMicrobial Sensitivity TestsPeroxidaseAnti-Bacterial AgentsCeriumCopperHydrogen PeroxidePeroxidaseReactive Oxygen SpeciesCu/Ce nanozymeCuproptosis-like deathFood preservationMRSA eradicationMulti-enzymatic activitiesROS scavenging

Identifiers

PMID41992299
PMCPMC13217961

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.