Evidence map›Paper›PMID 41992167›Full record

Observational studyBMC psychiatry2026

Intensive home treatment compared to inpatient psychiatric treatment: a 36-month follow-up of a propensity-score matched retrospective multicenter cohort study.

Konstantinos Nikolaidis, Sandeep Rout, Olaf Hardt, Christoph Richter, Britta Janßen, Jürgen Timm, Andreas Bechdolf

Abstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in BMC psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Konstantinos NikolaidisDepartment of Psychiatry, Psychotherapy, and Psychosomatics Incorporating FRITZ am Urban and Soulspace, Vivantes Hospital am Urban and Vivantes Hospital im Friedrichshain, Dieffenbachstr. 1, 10967, Berlin, Germany. konstantinos.nikolaidis@charite.de.ORCID 0009-0006-7755-9357
Sandeep RoutDepartment of Psychiatry, Psychotherapy and Psychosomatics, Vivantes Hospital Neukölln, Berlin, Germany.
Olaf HardtDepartment of Psychiatry, Psychotherapy and Psychosomatics, Vivantes Hospital Neukölln, Berlin, Germany.
Christoph RichterDepartment of Psychiatry and Psychotherapy, Charité Campus Mitte, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.
Britta JanßenDepartment of Psychiatry, Psychotherapy and Psychosomatics, Vivantes Hospital Kaulsdorf, Berlin, Germany.
Jürgen TimmCompetence Center for Clinical Studies Bremen, Department of Biometry, University of Bremen, Bremen, Germany.
Andreas BechdolfDepartment of Psychiatry, Psychotherapy, and Psychosomatics Incorporating FRITZ am Urban and Soulspace, Vivantes Hospital am Urban and Vivantes Hospital im Friedrichshain, Dieffenbachstr. 1, 10967, Berlin, Germany.ORCID 0000-0003-4796-3392

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntensive Home Treatment (IHT) has been implemented as an alternative to inpatient psychiatric treatment for selected patients requiring acute care. While short-term reductions in inpatient utilization have been reported, evidence on long-term outcomes beyond 12 months—particularly regarding readmissions, treatment days, and broader psychiatric service use—remains limited. This study evaluates the 36-month effectiveness of IHT compared to inpatient treatment (IT) in routine care, focusing on readmission rates, treatment days, and outpatient service engagement.

methodsWe conducted a retrospective propensity-score matched cohort study using routine clinical data from three psychiatric hospitals in Berlin, Germany. Patients receiving IHT were matched (1:1) to patients receiving IT based on age, gender, diagnosis, and prior service utilization. Outcomes included inpatient and combined readmissions (IT, IHT and day clinic), treatment days, time to readmission, and first-time use of the Psychiatric Outpatient Department (POD) over 36 months. Statistical analyses included binary logistic regression, Kaplan–Meier survival analysis with log-rank testing, and non-parametric tests.

results263 patients receiving IHT were matched to 263 patients treated with IT, with no statistical differences at baseline between groups. The IHT group had significantly lower inpatient readmission rates (41.1% vs. 55.5%, p = 0.001), fewer inpatient readmissions (mean 1.72 vs. 2.02, p = 0.005), and fewer inpatient days (48.5 vs. 51.7, p = 0.003) compared to IT over 36 months. Time to readmission was longer for IHT (median not reached vs. 610 days for IT, p = 0.001). Combined readmission rates (IHT + IT+day clinic) did not differ significantly (61.2% vs. 64.3%, p = 0.47). IHT patients were more likely to initiate for the first time a POD treatment (33.5% vs. 24.7%, p = 0.035) and had more IHT readmissions (mean 0.85 vs. 0.35, p < 0.001).

conclusionsIn this selected cohort of patients deemed suitable for home-based acute care, IHT was associated with fewer inpatient readmissions and a longer time to inpatient readmission over a 36-month follow-up period. Overall acute psychiatric care use (inpatient + IHT) did not differ between groups, suggesting that IHT may not reduce overall acute care need but may shift care from inpatient settings toward home-based treatment.These findings should be interpreted cautiously given the non-randomized study design and the likelihood of residual selection bias. Limitations include restricted generalizability to rural areas and lack of clinical symptom data. Further multi-centre studies are needed to confirm these results regarding long-term effects across diverse healthcare systems.

trial registrationGerman Clinical Trials Register (DRKS), DRKS00036833. Registered May 21, 2025, https://www.drks.de/search/de/trial/DRKS00036833/details .

Indexed as

Home Care ServicesHospitalizationMental DisordersAdultAgedFemaleFollow-Up StudiesHospitals, PsychiatricHumansMaleMiddle AgedPatient ReadmissionPropensity ScoreRetrospective StudiesTreatment OutcomeIntensive home treatmentPropensity score matchingPsychiatric service utilizationReadmission rates

Identifiers

PMID41992167
PMCPMC13085383

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.