Evidence map›Paper›PMID 41992142›Full record

ArticleBMC pregnancy and childbirth2026

Conservative management of placenta accreta spectrum disorders: a retrospective cohort study.

Simon Benoit Dubé, Dong Bach Nguyen, Cassandra Della Rocca, Jessica Papillon Smith, Fady W Mansour, Srinivasan Krishnamurthy, Richard Brown, Andrew Zakhari

Abstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Simon Benoit DubéDepartment of Obstetrics and Gynecology, McGill University Health Centre, Royal Victoria Hospital, Glen Site, 1001 Boulevard Decarie, Montreal, QC, H4A3J1, Canada.
Dong Bach NguyenDepartment of Obstetrics and Gynecology, McGill University Health Centre, Royal Victoria Hospital, Glen Site, 1001 Boulevard Decarie, Montreal, QC, H4A3J1, Canada.
Cassandra Della RoccaDepartment of Obstetrics and Gynecology, McGill University Health Centre, Royal Victoria Hospital, Glen Site, 1001 Boulevard Decarie, Montreal, QC, H4A3J1, Canada.
Jessica Papillon SmithDepartment of Obstetrics and Gynecology, McGill University Health Centre, Royal Victoria Hospital, Glen Site, 1001 Boulevard Decarie, Montreal, QC, H4A3J1, Canada.
Fady W MansourDepartment of Obstetrics and Gynecology, McGill University Health Centre, Royal Victoria Hospital, Glen Site, 1001 Boulevard Decarie, Montreal, QC, H4A3J1, Canada.
Srinivasan KrishnamurthyDepartment of Obstetrics and Gynecology, McGill University Health Centre, Royal Victoria Hospital, Glen Site, 1001 Boulevard Decarie, Montreal, QC, H4A3J1, Canada.
Richard BrownDepartment of Obstetrics and Gynecology, McGill University Health Centre, Royal Victoria Hospital, Glen Site, 1001 Boulevard Decarie, Montreal, QC, H4A3J1, Canada.
Andrew ZakhariDepartment of Obstetrics and Gynecology, McGill University Health Centre, Royal Victoria Hospital, Glen Site, 1001 Boulevard Decarie, Montreal, QC, H4A3J1, Canada. andrew.zakhari@mcgill.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlacenta Accreta Spectrum Disorders (PASD) are rare but life-threatening obstetric conditions characterized by abnormal placental adherence into or beyond the myometrium, resultant from previous uterine scarring, often rendering placental separation either impossible or associated with a significant risk of massive hemorrhage. As a result, caesarean hysterectomy is commonly performed following delivery, to manage associated complications. With the rising incidence of PASD paralleling the global increase in cesarean deliveries, there is a growing need to investigate and highlight fertility-preserving surgical alternatives. This study aimed to assess the rate of uterine preservation and maternal and fetal outcomes of conservatively managed placenta accreta spectrum disorders (PASD).

methodsThis retrospective cohort study was performed for conservatively managed patients with PASD at our center between January 2011 and February 2022. Cases were retrieved through operative bookings and codified delivery statistics from the birthing center. Necessary data was then collected through individual chart review.

resultsEleven patients underwent conservative management of PASD, of whom eight were delivered by elective caesarean, two by emergency cesarean, and one was an out-born post-partum transfer. A diagnosis of PASD was suspected antenatally in seven of the patients. Seven patients (63.6%) underwent expectant management, with the placenta left in situ, whereas the other four (36.4%) had extirpative or resective management. A total of 8 patients underwent embolization by interventional radiology immediately following their cesarean, and repeat embolization was performed in two patients. Of the 7 patients managed expectantly, three patients had spontaneous resolution of their residual placenta, three patients underwent interval hysterectomy within a range of 24 to 116 days, while the remaining patient required a curettage. The mean time to resolution of patients who underwent expectant management was 83 days.

conclusionsIn this study, 72.7% of conservatively managed cases of PASD avoided hysterectomy following caesarean delivery. While not without risks, conservative management of PASD can be offered to patients wishing to preserve fertility after individualized counselling.

Indexed as

Conservative TreatmentPlacenta AccretaAdultCesarean SectionFemaleFertility PreservationHumansHysterectomyPregnancyRetrospective StudiesWatchful WaitingCaesarean hysterectomyConservative treatmentExpectant managementFertility preservationMaternal outcomesObstetric labor complicationsPlacenta accreta spectrumPlacenta diseasesPlacental separationPregnancy complications

Identifiers

PMID41992142
PMCPMC13202961

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.