Evidence map›Paper›PMID 41992037›Full record

ArticleScientific reports2026

Temporal trends in cardiovascular disease and diabetes prevalence in the United States: assessing compression versus expansion.

Alberto Arletti, Lorenzo Schiavon, Mattia Stival, Michele Marzulli, Gaia Bertarelli, Stefano Campostrini

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In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Alberto ArlettiDepartment of Economics, Ca' Foscari University of Venice, Cannaregio 873, 30100, Venice, Italy. alberto.arletti@unive.it.
Lorenzo SchiavonDepartment of Economics, Ca' Foscari University of Venice, Cannaregio 873, 30100, Venice, Italy.
Mattia StivalDepartment of Economics, Ca' Foscari University of Venice, Cannaregio 873, 30100, Venice, Italy.
Michele MarzulliDepartment of Economics, Ca' Foscari University of Venice, Cannaregio 873, 30100, Venice, Italy.
Gaia BertarelliDepartment of Economics, Ca' Foscari University of Venice, Cannaregio 873, 30100, Venice, Italy.
Stefano CampostriniDepartment of Economics, Ca' Foscari University of Venice, Cannaregio 873, 30100, Venice, Italy.

Funding

European Commission Next Generation EU, Mission 4 Component 2, within the NRRP (National Recovery and Resilience Plan) project "Age-It - Ageing well in an ageing society" (PE0000015 - CUP H73C22000900006)
6 · The paper itself

Abstract

Recent trends from Western countries indicate a stagnation of life expectancy gains, raising questions about the mechanisms that sustain healthy aging and morbidity compression. In this study, we focus on trends in cardiovascular diseases and diabetes and their determinants in the United States, as relevant contributors to potential morbidity compression and, consequently, to increases in healthy life expectancy. Using data from the Behavioral Risk Factor Surveillance System from 1990 to 2023, we apply a pseudo-panel approach to analyze morbidity patterns across birth cohorts in the United States. The models account for covariates such as BMI, smoking, ethnicity, gender, income, and education, including relevant nonlinearities and interactions to capture heterogeneity in disease risk. Findings show that, at comparable ages, more recent cohorts exhibit higher disease risk, for diabetes, a pattern that is not consistent with morbidity compression. These results are largely explained by the growing presence of behavioral and socioeconomic risk factors, such as overweight and low income, which disproportionately affect younger cohorts. Our study contributes to the growing literature documenting worsening population health trajectories in countries with advanced medical systems and highlights the need for public health strategies that address both behavioral and structural determinants to promote healthy aging.

Indexed as

Cardiovascular DiseasesDiabetes MellitusAgedFemaleHumansLife ExpectancyMaleMiddle AgedPrevalenceRisk FactorsSocioeconomic Disparities in HealthSocioeconomic FactorsUnited StatesAgingBRFSSCohort analysisMorbidity compressionSocioeconomic inequalities

Identifiers

PMID41992037
PMCPMC13247148

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.