Article in Nature neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Stochastic choices in the retina and optic lobesR01EY013010 · NEI · NEW YORK UNIVERSITY · PI DESPLAN, CLAUDE · 1999 to 2025
$9.1M
Neurogenesis of the optic lobesR01EY017916 · NEI · NEW YORK UNIVERSITY · PI Claude Desplan · 2007 to 2026
$8.0M
Gene Regulatory Networks of Synaptic SpecificityR00NS125117 · NINDS · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI Mehmet Neset Ozel · 2024 to 2026
$740k
Understanding the regulation of neuron cell number and arbor sizeR00EY032269 · NEI · CITY COLLEGE OF NEW YORK · PI Jennifer A Malin · 2025 to 2026
$448k
Understanding the regulation of neuron cell number and arbor sizeK99EY032269 · NEI · NEW YORK UNIVERSITY · PI MALIN, JENNIFER A · 2021 to 2022
$281k
Deciphering the mechanisms underlying multicolumnar neuron pathfinding and specification in the Drosophila melanogaster optic lobeF32EY028012 · NEI · NEW YORK UNIVERSITY · PI MALIN, JENNIFER A · 2017 to 2019
$184k
Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada (NSERC Canadian Network for Research and Innovation in Machining Technology) RGPIN2015-06457EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 949500EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 Marie Sklodowska-Curie Actions (H2020 Excellent Science - Marie Sklodowska-Curie Actions) 101154260NEI NIH HHS F32 EY028012NEI NIH HHS K99 EY032269NEI NIH HHS R00 EY032269NEI NIH HHS R01 EY013010NEI NIH HHS R01 EY017916New York State Stem Cell Science (NYSTEM) C322560GGNew York University (NYU) MacCracken FellowshipNew York University (NYU) MacCracken Fellowship and Dean's Dissertation Ph.D. FellowshipNINDS NIH HHS R00 NS125117U.S. Department of Health & Human Services | NIH | National Eye Institute (NEI) F32EY028012U.S. Department of Health & Human Services | NIH | National Eye Institute (NEI) R01EY017916U.S. Department of Health & Human Services | NIH | National Eye Institute (NEI) R01EY13010U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) K99R00NS125117
6 · The paper itself
Abstract
In the medulla of the Drosophila optic lobe, the identity of each neuronal type is specified in progenitors and newborn neurons via the integration of temporal, spatial and Notch-driven patterning mechanisms. This identity is maintained in differentiating and adult neurons by the continuous expression of neuronal type-specific combinations of transcription factors called terminal selectors, which are thought to control all neuronal type-specific features. How the patterning mechanisms establish terminal selector expression is unknown. Here we have used single-cell mRNA sequencing to characterize the spatial origins of medulla neurons. Combined with our previous characterization of their temporal and Notch origins, this allowed us to identify correlations between patterning information, terminal selector expression and neuronal features. Our results suggest that different subsets of the patterning information accessible to a given neuronal type control the expression of each of its terminal selectors and modules of terminal features, including neurotransmitter identity.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Spatial, temporal and Notch determination of terminal selector expression controls neuronal cell fate in the Drosophila optic lobe. · full record | OpenQuestion