ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2026
Translation and validation of the Migraine Interictal Burden Scale (MIBS-4) in an Italian clinical cohort.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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- Two-Year Outcomes and Interictal Burden After Treatment for Medication Overuse Headache.Journal of clinical medicine · 2026Article
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Abstract
backgroundThe Migraine Interictal Burden Scale (MIBS-4) is a brief validated patient-reported measure of migraine interictal impact; however, an official Italian translation is not currently available.
methodsThe MIBS-4 was translated and culturally adapted into Italian language and psychometrically evaluated in adults with episodic or chronic migraine enrolled in the Italian Headache Registry (RICe). In a 4-week test–retest design, participants completed the Italian version of MIBS-4 and the Migraine Disability Assessment (MIDAS) at baseline (T0) and at follow up (T1). We assessed internal consistency, dimensionality, test–retest reliability, convergent validity, and known-groups validity across MIDAS disability grades.
resultsA total of 191 patients with migraine were included in test–retest analyses. Internal consistency was good to excellent (Cronbach’s α = 0.86 at T0; 0.90 at T1; ordinal α = 0.91–0.94; McDonald’s ω = 0.88–0.91). Parallel analysis supported a stable one-factor solution at both timepoints. Item-level agreement was moderate (weighted κ = 0.45–0.60; all p < 0.001), as was the total-score stability (ICC[A,1] = 0.62, 95% CI 0.50–0.72). Convergent validity with MIDAS was moderate (ρ = 0.40 at T0; ρ = 0.33 at T1; both p < 0.001). DISCUSSION: The present findings indicate that the Italian MIBS-4 is psychometrically robust and captures a dimension of migraine burden that is only partially explained by conventional attack-focused disability measures.
conclusionThe Italian version of MIBS-4 provides a reliable instrument for quantifying interictal burden in Italian-speaking migraine individuals, enabling a more comprehensive evaluation of migraine and supporting individualized management.
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