Evidence map›Paper›PMID 41991815›Full record

ReviewArchives of pharmacal research2026

Glycosides in Meliaceae and Rutaceae sources: phytochemistry and pharmacological activities.

Risma Rahmawati, Al Arofatus Naini, Sofa Fajriah, Sri Rahayu, Nurlelasari, Unang Supratman

Abstract readReview
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In one paragraph

Review in Archives of pharmacal research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Risma RahmawatiDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Sumedang, West Java, Indonesia.
Al Arofatus NainiResearch Center for Pharmaceutical Ingredients and Traditional Medicine, National Research and Innovation Agency (BRIN), Cibinong Science Center Complex - BRIN, Cibinong, Bogor, 16911, West Java, Indonesia.
Sofa FajriahResearch Center for Pharmaceutical Ingredients and Traditional Medicine, National Research and Innovation Agency (BRIN), Cibinong Science Center Complex - BRIN, Cibinong, Bogor, 16911, West Java, Indonesia.
Sri RahayuResearch Center for Applied Botany, National Research and Innovation Agency (BRIN), Cibinong Science Center Complex - BRIN, Cibinong, Bogor, 16911, West Java, Indonesia.
NurlelasariDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Sumedang, West Java, Indonesia.
Unang SupratmanDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Sumedang, West Java, Indonesia. unang.supratman@unpad.ac.id.ORCID http://orcid.org/0000-0003-1104-2321

Funding

Universitas Padjadjaran No. 5713/UN6.3.1/PT.00/2025
6 · The paper itself

Abstract

Glycosides are widely distributed plant secondary metabolites and constitute an important source of chemical diversity in Meliaceae and Rutaceae families. Therefore, this review aimed to compile glycosides reported from Meliaceae and Rutaceae families over four decades of investigation (1983-2024), covering flavonoid, aromatic, terpenoid, and other structurally distinct groups. Across these classes, reported biological activities included antioxidant, anti-inflammatory, antimicrobial, and cytotoxic effects, and other activities. The result showed that after comparing available data, biological activity was largely associated with aglycone framework, while glycosylation mainly contributed to structural diversification and influenced physicochemical properties such as solubility and stability. By collecting phytochemical classifications and reported bioactivity data, this review focused on clarifying general trends in glycoside distribution in Meliaceae and Rutaceae, thereby bridging the knowledge gaps in structure-activity relationships and pharmacological evaluation.

Indexed as

GlycosidesPhytochemicalsPlant ExtractsRutaceaeAnimalsAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsHumansStructure-Activity RelationshipAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsGlycosidesPhytochemicalsPlant ExtractsAntioxidant activitiesCytotoxic activitiesGlycosidesMeliaceaeRutaceae

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.