Evidence map›Paper›PMID 41991679›Full record

SynthesisEvidence-based dentistry2026

Do systematic reviews of non- and micro-invasive treatment for caries lesions in children and adolescents adhere to the PRISMA reporting guidelines? A meta-research.

Caroline Mariano Laux, Rokaia Ahmed Elagami, Adriana Esteves Santos, Tamara Kerber Tedesco, Daniela Prócida Raggio

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Evidence-based dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Caroline Mariano LauxDepartment of Orthodontics and Pediatric Dentistry, Faculty of Dentistry, University of São Paulo, São Paulo, Brazil.
Rokaia Ahmed ElagamiDepartment of Orthodontics and Pediatric Dentistry, Faculty of Dentistry, University of São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-7238-4598
Adriana Esteves SantosDepartment of Orthodontics and Pediatric Dentistry, Faculty of Dentistry, University of São Paulo, São Paulo, Brazil.
Tamara Kerber TedescoDepartment of Orthodontics and Pediatric Dentistry, Faculty of Dentistry, University of São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-0794-1578
Daniela Prócida RaggioDepartment of Orthodontics and Pediatric Dentistry, Faculty of Dentistry, University of São Paulo, São Paulo, Brazil. danielar@usp.br.ORCID http://orcid.org/0000-0002-0048-2068

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate whether systematic reviews (SRs) with or without meta-analysis or network meta-analysis focusing on non- and micro-invasive treatment of caries lesions in children and adolescents adhere to the PRISMA reporting guidelines and the PRISMA checklist and their extensions for Abstracts and Network Meta-analysis (NMA). MATERIAL AND

methodsWe conducted a comprehensive literature search up to 1st of September 2025 in the following databases: PubMed/MEDLINE, Scopus, Web of Science, and EMBASE. Gray literature was assessed through ProQuest and Epistemonikos, with no language or publication date restrictions. We included SRs focused on non- and micro-invasive caries treatment and excluded study protocols of SRs and SRs focused on special populations. Two independent reviewers extracted data from the included systematic reviews and assessed the adherence to PRISMA and its extensions as a reporting guideline.

resultsWe retrieved 1221 publications; after duplicate removal and eligibility process, 45 studies were considered for further data extraction and 36 SRs for the assessment of the adherence to the PRISMA checklists. Two independent reviewers assessed the adherence to the PRISMA checklist, and the mean overall adherence was 70.8%. Thirty-six SRs (80%) reported following PRISMA. The PRISMA item with the lowest adherence was protocol pre-registration (n = 2; 12.5%). In contrast, the SRs reported following the PRISMA-NMA extension showed higher adherence to the checklist items.

conclusionsDespite the authors' declaration of adhering to PRISMA, several reporting items were not fully addressed in the systematic reviews on non- and micro-invasive caries treatments. Incomplete or inconsistent reporting limits clinicians' ability to interpret the sources of discordant findings across reviews and constrains the application of evidence-based judgments in pediatric caries management. Given the overall low reporting quality, not only is further improvement in these SRs essential, but some recommended management strategies should also be interpreted and implemented with caution until more robust and transparently reported evidence becomes available.

Indexed as

Dental CariesGuideline AdherenceSystematic Reviews as TopicAdolescentChecklistChildHumans

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.