Evidence map›Paper›PMID 41991616›Full record

ArticleEMBO reports2026

A call for preregistration of in vitro research : Pregistration as a tool to improve reproducibility and transparency.

Céline Heinl, Nuno H Franco, Bettina Bert, Katherina Siewert, Dania Movia, Edlira Aruçi, Carina Ladeira, Ahmed Y Sanin, Winfried Neuhaus, Ulf D Kahlert and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EMBO reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Céline HeinlGerman Centre for the Protection of Laboratory Animals (Bf3R) at the German Federal Institute for Risk Assessment (BfR), Berlin, Germany. celine.heinl@bfr.bund.de.ORCID http://orcid.org/0000-0003-3369-1939
Nuno H Francoi3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.ORCID http://orcid.org/0000-0003-4015-0532
Bettina BertGerman Centre for the Protection of Laboratory Animals (Bf3R) at the German Federal Institute for Risk Assessment (BfR), Berlin, Germany.ORCID http://orcid.org/0000-0002-8202-9290
Katherina SiewertDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.ORCID http://orcid.org/0000-0003-0380-1594
Dania MoviaDepartment of Biology and Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Callan Building, Maynooth, Ireland.ORCID http://orcid.org/0000-0001-6412-8132
Edlira AruçiDepartment of Biotechnologies, Chemistry and Pharmacy, University of Siena, Siena, Italy.ORCID http://orcid.org/0009-0009-3412-526X
Carina LadeiraEscola Superior de Saúde de Lisboa, Polytechnic University of Lisbon, Lisbon, Portugal.ORCID http://orcid.org/0000-0001-5588-0074
Ahmed Y SaninMedical Faculty and University Medical Center Magdeburg, Clinic for General-, Visceral-, Vascular-, and Transplantation Surgery, Magdeburg, Germany.ORCID http://orcid.org/0009-0009-7786-2200
Winfried NeuhausCompetence Unit Molecular Diagnostics, Center for Health and Bioresources, AIT-Austrian Institute of Technology GmbH, Vienna, Austria.ORCID http://orcid.org/0000-0002-6552-7183
Ulf D KahlertMedical Faculty and University Medical Center Magdeburg, Clinic for General-, Visceral-, Vascular-, and Transplantation Surgery, Magdeburg, Germany.ORCID http://orcid.org/0000-0002-6021-1841
Manosij GhoshDepartment of Public Health and Primary Care, Centre for Environment and Health, Katholieke Universiteit Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0001-5034-001X
Aurélie ThomasAnimal Sciences & Technology, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK.ORCID http://orcid.org/0000-0003-1655-3278
Athanassia SotiropoulosInserm, GIS FC3R, 94700, Maisons-Alfort, France.ORCID http://orcid.org/0000-0002-7265-1473

Funding

European Cooperation in Science and Technology (COST) CA21139
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41991616
PMCPMC13171870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.