Evidence map›Paper›PMID 41991614›Full record

ArticleScientific reports2026

Natural antisense transcript Nat9a suppresses Scn9a (Na

Shengnan Li, Sonia Santana-Varela, Hajar Mikaeili, Abdella M Habib, Janvi Patel, Naxi Tian, Andrei L Okorokov, James J Cox

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shengnan Li *Wolfson Institute for Biomedical Research, Division of Medicine, University College London, Gower Street, London, WC1E 6BT, UK.
Sonia Santana-Varela *Wolfson Institute for Biomedical Research, Division of Medicine, University College London, Gower Street, London, WC1E 6BT, UK.
Hajar Mikaeili *Wolfson Institute for Biomedical Research, Division of Medicine, University College London, Gower Street, London, WC1E 6BT, UK.
Abdella M HabibCollege of Medicine, QU Health, Qatar University, PO Box 2713, Doha, Qatar.
Janvi PatelWolfson Institute for Biomedical Research, Division of Medicine, University College London, Gower Street, London, WC1E 6BT, UK.
Naxi TianWolfson Institute for Biomedical Research, Division of Medicine, University College London, Gower Street, London, WC1E 6BT, UK.
Andrei L OkorokovWolfson Institute for Biomedical Research, Division of Medicine, University College London, Gower Street, London, WC1E 6BT, UK. a.okorokov@ucl.ac.uk.
James J CoxWolfson Institute for Biomedical Research, Division of Medicine, University College London, Gower Street, London, WC1E 6BT, UK. j.j.cox@ucl.ac.uk.

Funding

Medical Research Council MR/R011737/1Qatar National Research Fund NPRP13S-0209-200315Qatar University QUSD-CMED-2018/9-3Wellcome 200183/Z/15/Z
6 · The paper itself

Abstract

Natural antisense transcripts (NATs) are important spatial and temporal regulators of gene expression. We previously cloned a NAT (Nat9a) to Scn9a, which encodes the Na

Indexed as

NAV1.7 Voltage-Gated Sodium ChannelNeuronsParvalbuminsProprioceptionRNA, AntisenseAnimalsGanglia, SpinalGene Expression RegulationMiceMice, KnockoutNAV1.1 Voltage-Gated Sodium ChannelPromoter Regions, GeneticSpinal CordNAV1.1 Voltage-Gated Sodium ChannelNAV1.7 Voltage-Gated Sodium ChannelParvalbuminsRNA, AntisenseScn9a protein, mouseLong non-coding RNANatural antisense transcriptNaV1.1NaV1.7Pain insensitivityProprioceptionScn1aScn9a

Identifiers

PMID41991614
PMCPMC13247247

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.