Evidence map›Paper›PMID 41991206›Full record

ArticleThe European respiratory journal2026

The impact of neighbourhood material and social disadvantage on respiratory health across Canada.

Mira A Russell, Xuan Li, Dany Doiron, Gillian C Goobie, Jean Bourbeau, Wan C Tan, Miranda Kirby, Michael K Stickland, Dennis Jensen, Janice M Leung and 1 more

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Article in The European respiratory journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Mira A RussellDivision of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Xuan LiCentre for Heart Lung Innovation, St Paul's Hospital, University of British Columbia, Vancouver, BC, Canada.ORCID https://orcid.org/0009-0004-1337-3049
Dany DoironDepartment of Environmental and Occupational Health, School of Public Health, Université de Montréal, Montreal, QC, Canada.
Gillian C GoobieDivision of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.ORCID https://orcid.org/0000-0001-7982-5635
Jean BourbeauRespiratory Epidemiology and Clinical Research Unit, Research Institute of the McGill University Health Centre, Montreal, QC, Canada.ORCID https://orcid.org/0000-0002-7649-038X
Wan C TanDivision of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Miranda KirbyDepartment of Physics, Toronto Metropolitan University, Toronto, ON, Canada.ORCID https://orcid.org/0000-0003-2951-784X
Michael K SticklandDivision of Pulmonary Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Dennis JensenClinical Exercise and Respiratory Physiology Laboratory, Department of Kinesiology and Physical Education, McGill University, Montreal, QC, Canada.
Janice M LeungDivision of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, BC, Canada Janice.Leung@hli.ubc.ca.
CanCOLD Collaborative Research Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile smoking and genetic predisposition are known to confer an increased risk of lung diseases, less is known about the socioeconomic determinants of respiratory health. Disadvantages experienced at the neighbourhood level may contribute to poor lung outcomes. Our objective was to quantify the impact of neighbourhood disadvantage on respiratory outcomes in a general population cohort.

methods1449 adults enrolled in the Canadian Cohort Obstructive Lung Disease (CanCOLD) study were followed for 3 years with repeat pulmonary function and cardiopulmonary exercise testing. Chest computed tomography (CT) imaging was obtained at baseline. The Material and Social Deprivation Index was used to measure neighbourhood disadvantage. Regression models were used to quantify the association between neighbourhood disadvantage and pulmonary function, peak exercise capacity, quantitative CT measures, respiratory symptom scores, respiratory-related exacerbation events and mortality.

resultsWhen compared to individuals residing in neighbourhoods with the highest privilege, those residing in the most materially and socially disadvantaged neighbourhoods had significantly worse forced expiratory volume in 1 s (FEV

conclusionsResidence in the most materially and socially disadvantaged neighbourhood is associated with worse lung function and exercise outcomes, highlighting a population particularly vulnerable to chronic airways diseases.

Indexed as

Neighborhood CharacteristicsPulmonary Disease, Chronic ObstructiveResidence CharacteristicsAdultAgedCanadaCohort StudiesExercise TestFemaleForced Expiratory VolumeHumansLungMaleMiddle AgedOxygen ConsumptionRespiratory Function Tests

Identifiers

PMID41991206
PMCPMC13392455

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.