Evidence map›Paper›PMID 41990365›Full record

Trial reportTranslational behavioral medicine2026

Evaluating an online-delivered resistance exercise intervention for racially diverse breast cancer survivors using the RE-AIM framework.

Isabel L Wakefield, Océane Streubel, Adana A M Llanos, Shawna V Hudson, Kathryn Schmitz, Siobhan M Phillips, Sharon L Manne, N Lynn Henry, Ken Resnicow, Angela J Fong

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Translational behavioral medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04562233 (Breast Cancer and Resistance Exercise Program), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04562233 naterminatednot on this map

Breast Cancer and Resistance Exercise Program (B-REP): A Feasibility and Acceptability Trial

TypeinterventionalSponsorRutgers, The State University of New JerseyRan2020 to 2023Enrolled56ConditionsBreast Cancer, Resistance TrainingArmsOnline-delivered physical activity intervention., Printed, individualized resistance-based physical activity program.
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Isabel L WakefieldSchool of Kinesiology, University of Michigan, Ann Arbor, MI, United States.ORCID 0009-0002-5515-2055
Océane StreubelSchool of Kinesiology, University of Michigan, Ann Arbor, MI, United States.
Adana A M LlanosDepartment of Epidemiology, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY, United States.ORCID 0000-0001-9954-9121
Shawna V HudsonInstitute for Health, Health Care Policy and Aging Research, Robert Wood Johnson Medical School, New Brunswick, NJ, United States.ORCID 0000-0002-7026-0743
Kathryn SchmitzHillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, United States.ORCID 0000-0003-2400-2935
Siobhan M PhillipsNorthwestern University Feinberg School of Medicine, Chicago, IL, United States.ORCID 0000-0001-8899-3825
Sharon L ManneDivision of Population Sciences, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, United States.ORCID 0000-0002-9304-7822
N Lynn HenryDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, United States.ORCID 0000-0002-4771-5930
Ken ResnicowSchool of Public Health, University of Minnesota, Minneapolis, MN, United States.ORCID 0000-0003-1416-9627
Angela J FongSchool of Kinesiology, University of Michigan, Ann Arbor, MI, United States.ORCID 0000-0002-8825-6427

Funding

Rutgers Cancer Institute and RWJ Barnabas Health Mission Support
6 · The paper itself

Abstract

backgroundBreast cancer survivors (BCS) experience persistent physical and psychological effects after treatment, with racially diverse groups demonstrating lower adherence to cancer-specific resistance exercise guidelines. Online resistance exercise interventions show promise for enhancing accessibility and health outcomes among BCS. However, evidence regarding their feasibility of implementation remains limited. Yet, such information is critical for assessing scalability and implementation in non-laboratory settings. PURPOSE: Using the RE-AIM (reach, efficacy, adoption, implementation, and maintenance) framework, this study evaluated the reach, efficacy, adoption, and implementation of a 12-week, supervised, online resistance exercise intervention for racially diverse BCS.

methodsA mixed methods approach with a pre-post-study design was used. Quantitative outcomes included sociodemographic representativeness (reach), physical function (efficacy), and session fidelity (implementation). Qualitative interviews examined participant experiences, barriers, and facilitators (adoption).

resultsThe intervention enrolled a racially diverse BCS sample (N = 47; 57.4% White, 23.4% Black, 14.8% Asian) that was mostly representative of the host institution catchment area, though participants had higher education levels. The intervention group demonstrated statistically significant improvements in upper- (P = .009) and lower-body physical function (P = .003) versus control, only. Adoption facilitators included program convenience, accessibility of online delivery, and trainer support, while barriers were equipment challenges, competing priorities, and cancer-related side effects. Program implementation fidelity was high for core components.

conclusionsKey factors contributed to the feasibility of implementation of the intervention. Future remote exercise interventions should address equipment needs, individualized support, and tailored recruitment to enhance adoption and facilitate scalability in non-laboratory settings. CLINICAL TRIAL INFORMATION: The Clinical Trials Registration #NCT04562233.

Indexed as

Breast NeoplasmsCancer SurvivorsResistance TrainingAdultAgedAsianBlack or African AmericanFemaleHumansMiddle AgedRacial GroupsWhitebreast cancer survivorsimplementation scienceonline interventionRE-AIM frameworkresistance exercise

Identifiers

PMID41990365
PMCPMC13448720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.