Evidence map›Paper›PMID 41989959›Full record

SynthesisGerontology2026

Efficacy and Safety of Hospital-at-Home versus Traditional Hospital Care in Older Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Hongyao He, Yajie Li, Yaqin Li, Xiaomin Xu, Qiuyan Fu, Xuemei Peng, Gang Yuan, Wen He, Ling Zhang, Zhexin Lin and 1 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Gerontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hongyao HeGeriatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yajie LiTrauma and Neurocritical Care Ward, Nangyang Central Hospital, Nanyang, China.
Yaqin LiGeriatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Xiaomin XuGeriatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Qiuyan FuGeriatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Xuemei PengGeriatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Gang YuanGeriatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Wen HeGeriatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Ling ZhangGeriatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Zhexin LinGeriatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, linzhx27@mail.sysu.edu.cn.
Miaohong ChenGeriatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, chmiaoh@mail.sysu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<p>Introduction: This systematic review and meta-analysis aimed to evaluate the effectiveness and safety of the Hospital-at-Home (HaH) model compared to traditional hospital care for older patients.

methodsWe comprehensively searched PubMed, Embase, Medline, Cochrane Library, SinoMed, Scopus, and <ext-link ext-link-type="uri" xlink:href="http://ClinicalTrials.gov" xmlns:xlink="http://www.w3.org/1999/xlink">ClinicalTrials.gov</ext-link> for randomized controlled trials (RCTs) published up to April 15, 2024. The primary outcomes were length of stay (LOS) and readmission rates. Secondary outcomes included total cost, mortality, adverse events, and instrumental activities of daily living (IADL).

resultsEleven RCTs involving 3,301 patients were included. The HaH group demonstrated a significantly shorter LOS (SMD = -0.45; 95% CI: -0.62 to -0.28; p < 0.01) and lower total healthcare costs (SMD = -0.40; 95% CI: -0.52 to -0.28; p < 0.0001) than the traditional care group. HaH was also associated with a reduced risk of readmission, with subgroup analyses showing consistent benefits at 1, 3, and 9 months. Additionally, patients receiving HaH showed modest but significant improvements in IADL scores (SMD = -0.15; 95% CI: -0.26 to -0.04; p < 0.0001). However, no significant differences were found between the two groups in terms of mortality (RR = 1.03; 95% CI: 0.49-2.18; p = 0.93) or adverse event rates (RR = 1.01; 95% CI: 0.43-2.36; p = 0.084).

conclusionFor a selected group of older patients, HaH appears to be a viable alternative to traditional hospitalization, offering advantages in reducing LOS, healthcare costs, and readmission rates, while potentially improving functional recovery without increasing risks to patient safety. Further research is warranted to confirm these findings and refine implementation strategies. </p>.

Indexed as

Home Care Services, Hospital-BasedHospitalizationActivities of Daily LivingAgedAged, 80 and overHumansLength of StayPatient ReadmissionRandomized Controlled Trials as TopicAgedHospital-at-HomeInpatientRandomize controlled trials

Identifiers

PMID41989959
PMCPMC13160507

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.