Evidence map›Paper›PMID 41989588›Full record

ReviewArchives of microbiology2026

Interactions between bacterial microbiota and protozoan parasites: an intimate relationship.

Raquel Aguilar-Rosales, Alma Reyna Escalona-Montaño, Ana Pamela Gómez-García, Daniel Andrés Sánchez-Almaraz, Martha Legorreta-Herrera, Omar Fernández-Rivera, María Magdalena Aguirre-Garcia

Abstract readReview
In one paragraph

Review in Archives of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Raquel Aguilar-RosalesUnidad de Investigación, UNAM-INC, División de Investigación, Facultad de Medicina, UNAM, Instituto Nacional de Cardiología Ignacio Chavéz, 14080, Ciudad de México, Mexico.ORCID http://orcid.org/0009-0007-8236-2986
Alma Reyna Escalona-MontañoUnidad de Investigación, UNAM-INC, División de Investigación, Facultad de Medicina, UNAM, Instituto Nacional de Cardiología Ignacio Chavéz, 14080, Ciudad de México, Mexico.ORCID http://orcid.org/0000-0002-0060-2939
Ana Pamela Gómez-GarcíaThoracic Oncology Unit, Instituto Nacional de Cancerología (INCan), 14080, Ciudad de México, Mexico.ORCID http://orcid.org/0000-0002-9392-1647
Daniel Andrés Sánchez-AlmarazUnidad de Investigación, UNAM-INC, División de Investigación, Facultad de Medicina, UNAM, Instituto Nacional de Cardiología Ignacio Chavéz, 14080, Ciudad de México, Mexico.ORCID http://orcid.org/0000-0003-1304-3926
Martha Legorreta-HerreraLaboratorio de Inmunología Molecular, Unidad de Investigación Química Computacional, Síntesis y Farmacología en Moléculas de Interés Biológico, División de Estudios de Posgrado e Investigación, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México (UNAM), 09230, Ciudad de México, Mexico.ORCID http://orcid.org/0000-0001-5985-7365
Omar Fernández-RiveraLaboratorio de Inmunología Molecular, Unidad de Investigación Química Computacional, Síntesis y Farmacología en Moléculas de Interés Biológico, División de Estudios de Posgrado e Investigación, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México (UNAM), 09230, Ciudad de México, Mexico.ORCID http://orcid.org/0009-0005-0271-2591
María Magdalena Aguirre-GarciaUnidad de Investigación, UNAM-INC, División de Investigación, Facultad de Medicina, UNAM, Instituto Nacional de Cardiología Ignacio Chavéz, 14080, Ciudad de México, Mexico. maguirre@unam.mx.ORCID http://orcid.org/0000-0001-8696-9995

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interactions between parasites and the gut microbiota play a key role in immune responses and susceptibility to zoonotic diseases; however, many aspects of how protozoan infections alter microbial diversity and how these changes influence parasite pathogenicity and host defense remain poorly understood. This review integrates recenst studies using murine models of the Muroidea superfamily, highlighting patterns in microbial diversity, functional interactions, and potential immunometabolic mechanisms underlying these relationships. Both consistent findings and discrepancies among studies are identified, reflecting differences in parasite species, experimental models, and infection conditions. Unlike previous work, this review emphasizes the link between microbiota alterations, infection progression, and host responses. Finally, these findings are integrated to provide an interpretive framework that advances our understanding of how the microbiota modulates infection dynamics and identifies key knowledge gaps that warrant further investigation.

Indexed as

Gastrointestinal MicrobiomeHost-Parasite InteractionsMicrobiotaParasitesProtozoan InfectionsAnimalsBacteriaHumansMiceAnimal microbiotaGut microbiotaMicrobiotaMurineParasitesProtozoa

Identifiers

PMID41989588
PMCPMC13086732

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.