Evidence map›Paper›PMID 41989516›Full record

ArticleInsights into imaging2026

Force-controlled robotic ultrasound elastography enhances diagnostic consistency for thyroid nodules.

Tianhui Yan, Xu Le, Li Xie, Xiangyu Qiu, Delei Cheng, Chong Pei, Lei Hu

Abstract read
In one paragraph

Article in Insights into imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Tianhui Yan *Department of Ultrasound, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Xu Le *Department of Ultrasound, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Li Xie *Department of Ultrasound, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Xiangyu QiuDepartment of Ultrasound, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Delei ChengDepartment of Interventional Radiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Chong PeiDepartment of Respiratory and Critical Care Medicine, The First People's Hospital of Hefei City, The Third Affiliated Hospital of Anhui Medical University, Hefei, China. pchl331@126.com.
Lei HuDepartment of Ultrasound, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. hulei@ustc.edu.cn.ORCID http://orcid.org/0000-0002-6871-3547

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess whether a force-controlled robotic arm can improve image quality, consistency, and diagnostic accuracy of strain elastography (SE) and shear wave elastography (SWE) in differentiating benign from malignant thyroid nodules. MATERIALS AND

methodsIn this prospective study, 131 thyroid nodules were examined by a junior physician, a senior physician, and a robotic arm with a PID-based force feedback system. Image quality was evaluated using the structural similarity index (SSIM), peak signal-to-noise ratio (PSNR), mean squared error (MSE) and mean opinion score (MOS). Consistency was assessed with the Dice similarity coefficient (DSC) and the intraclass correlation coefficient (ICC) for SWE-derived Emax. Diagnostic performance was analyzed via ROC curves and AUC comparisons.

resultsThe robotic arm achieved higher image quality (SSIM up to 0.94, PSNR 42.25 dB, MSE 3.06) and MOS scores (SE: 4.1 ± 0.3; SWE: 4.3 ± 0.2) than both human operators (all p < 0.001). It also showed better consistency (DSC up to 0.90; ICC up to 0.94) and diagnostic accuracy (AUC 0.90 for SE, 0.95 for SWE; p < 0.05).

conclusionThe force-controlled robotic arm provides standardized, reproducible thyroid elastography with superior quality, consistency, and accuracy compared with manual scanning. CRITICAL RELEVANCE STATEMENT: This study explores robotic-assisted elastography to improve consistency in thyroid nodule assessment. KEY POINTS: The force-controlled robotic arm enhanced ultrasound elastography by generating clearer, more standardized images compared with manual acquisition. The force-controlled robotic arm scanning achieved superior intra-operator reproducibility. Diagnostic performance in differentiating benign from malignant thyroid nodules was significantly improved with robotic elastography, exceeding that of both junior and senior radiologists.

Indexed as

Force-controlled robotic armShear wave elastographyStrain elastographyThyroid noduleUltrasound elastography

Identifiers

PMID41989516
PMCPMC13087058

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.