Evidence map›Paper›PMID 41989438›Full record

ArticleNeuropsychology2026

Everyday executive functions in children with neurofibromatosis type 1: Data from nine institutions.

Xiaoli Zong, Dan Liu, Xian Wu, Pamela L Wolters, Jonathan M Payne, Bonita P Klein-Tasman, Karin S Walsh, Jennifer Janusz, Natalie Pride, Stephanie M Morris and 3 more

Abstract read
In one paragraph

Article in Neuropsychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xiaoli ZongDepartment of Medical Psychology, Army Medical University.ORCID 0000-0003-2167-4584
Dan LiuDepartment of Behavioral Sciences and Social Medicine, College of Medicine, Florida State University.
Xian WuDepartment of Behavioral Sciences and Social Medicine, College of Medicine, Florida State University.
Pamela L WoltersPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute.
Jonathan M PayneMurdoch Children's Research Institute.
Bonita P Klein-TasmanDepartment of Psychological and Brain Science, College of Letters and Science, University of Wisconsin-Milwaukee.
Karin S WalshChildren's National Hospital, George Washington University School of Medicine.
Jennifer JanuszChildren's Hospital Colorado, University of Colorado School of Medicine.
Natalie PrideChildren's Hospital at Westmead.
Stephanie M MorrisCenter for Autism and Related Disorders, Kennedy Krieger Institute.
Carrie E BeardenDepartment of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles.
Peter L StavinohaDepartment of Pediatrics Patient Care, Division of Pediatrics, University of Texas Monroe Dunaway Anderson Cancer Center.
Yang HouDepartment of Behavioral Sciences and Social Medicine, College of Medicine, Florida State University.ORCID 0000-0002-7360-5751

Funding

Pediatric Oncology Branch Behvioral Science CoreZIDBC011517 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI GLOD, JOHN · 2013 to 2025
$15.6M
Sleep and Circadian Dysfunction, Brain and Neurobehavioral Development in AutismP50HD103538 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Stewart H Mostofsky · 2020 to 2026
$9.9M
Florida State UniversityIntramural NIH HHS ZID BC011517National Institutes of Health; National Cancer InstituteNICHD NIH HHS P50 HD103538University of KentuckyUS Department of Defense; Congressionally Directed Medical Research Programs
6 · The paper itself

Abstract

objectiveExecutive function (EF) difficulties are prevalent in neurogenetic syndromes such as Neurofibromatosis Type 1 (NF1), the most common autosomal dominant condition associated with nervous system tumors. However, age-related differences in EF problems in children with NF1 remain poorly understood. This study aimed to examine how EF problems in daily life vary across ages throughout childhood and adolescence and how these age patterns vary across demographic and NF1 disease-related characteristics.

methodThis study integrated data of 1,294 observations from 1,025 children with NF1 (

resultsChildren with NF1 demonstrated elevated EF problems compared to the normative mean from early childhood through late adolescence, with deviations generally largest from midchildhood through midadolescence. At ages showing the greatest deviations from the normative mean, medium to large EF gaps were observed across five core domains (Cohen's

conclusionsLeveraging the largest EF data set of children with NF1 to date, this study precisely estimated EF problems across developmental periods and highlighted the heterogeneity in EF age patterns. These age-specific estimates are crucial for establishing EF developmental norms that guide clinical practice and patient management strategies. The findings can inform the design of individualized intervention and prevention strategies tailored to various developmental periods and diverse demographic and disease-related characteristics for children with NF1. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

Identifiers

PMID41989438
PMCPMC13089308

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.