ArticleArchives of rheumatology2026
Juvenile vs. Adult-Onset Spondyloarthritis: Uncovering Similarities and Differences.
Article in Archives of rheumatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsThe primary objective of this investigation is to systematically assess the resemblances and distinctions between enthesitisrelated arthritis (ERA), which serves as a pediatric analog to ankylosing spondylitis (AS), and AS. MATERIALS AND
methodsA cross-sectional analysis was conducted within a pediatric rheumatology facility and an adult rheumatology institution. Demographic and clinical attributes were juxtaposed between individuals diagnosed with AS and those with ERA.
resultsA cumulative total of 200 subjects (101 minors, 99 adults) were scrutinized. The prevalence of peripheral arthritis was significantly elevated in ERA (54.5%) compared to AS (21.2%, P < .001), whereas sacroiliitis, axial involvement, and morning stiffness were more prevalent in AS. Nonsteroidal anti-inflammatory drugs constituted the predominant initial therapeutic approach (99% vs. 91.9%, P = .01). Patients with ERA exhibited a higher utilization of corticosteroids (35.6% vs. 11.1%, P < .001) and diseasemodifying antirheumatic drugs (DMARDs) (87.1% vs. 60.6%, P < .001), with no notable variance in the application of biological agents. At the final follow-up assessment, 24.8% of ERA patients were free from medication, whereas no AS patients achieved a medication-free status.
conclusionAn increased volume of scientific evidence is requisite concerning the attributes of ERA, which is presently regarded predominantly within the framework of juvenile spondyloarthritis, distinguishing it from its adult counterpart; this study serves as an observational cohort investigation that underscores this imperative. Despite the observable differences and similarities between ERA and AS, further extensive studies incorporating inflammatory biomarkers are essential to ascertain whether these conditions represent discrete diseases or exist within a broader disease continuum. Cite this article as: Unan MK, Özaslan Z, Dilek G, Şahin N, Sönmez HE, Nas K. Juvenile vs. adult-onset spondyloarthritis: Uncovering similarities and differences. Arch Rheumatol. 2026;41(2):90-99.
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Registered trials
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