Evidence map›Paper›PMID 41989304›Full record

SynthesisActa orthopaedica2026

Migration patterns of uncemented femoral stems in hip replacement: a systematic review and meta-analysis of clinical radiostereometric analysis cohort studies.

Lisa Van der Water, Christiaan H Righolt, Trevor Gascoyne, Bart L Kaptein, Rob G H H Nelissen, Bart G C W Pijls

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Acta orthopaedica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lisa Van der WaterDepartment of Orthopaedics, Leiden University Medical Center, Leiden, the Netherlands. l.van_der_water@lumc.nl.
Christiaan H RigholtOrthopaedic Innovation Centre, Winnipeg, MB; Department of Surgery, University of Manitoba, Winnipeg, MB; Biomedical Engineering Program, University of Manitoba, Winnipeg, MB, Canada.ORCID 0000-0002-8472-932X
Trevor GascoyneOrthopaedic Innovation Centre, Winnipeg, MB, Canada.
Bart L KapteinDepartment of Orthopaedics, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0001-8772-9985
Rob G H H NelissenDepartment of Orthopaedics, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0003-1228-4162
Bart G C W PijlsDepartment of Orthopaedics, Leiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0001-5351-5057

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeWe conducted a systematic review and meta-analysis of radiostereometric analysis studies of primary uncemented femoral stems to investigate their subsidence and retroversion patterns and the migration patterns according to implant, patient, and study characteristics.

methodsA systematic search of PubMed, Web of Science, Cochrane, and Embase databases to identify all radiostereometric analysis studies on femoral stem migration following primary uncemented total hip replacement was performed. Clinical studies with 2 or more postoperative radiostereometric measurements within 2 years were included. Subsidence and retroversion at 6 weeks, 3 and 6 months, 1, 2, 5, and 10 years were included for analysis. Extracted implant characteristics included implant design, coating, and surgical approach. Data was analyzed using a random effects model.

results73 studies on 120 cohorts and 2,970 uncemented stems were included. 119 cohorts reported on subsidence and 91 on retroversion. The pooled subsidence at 3 months was 0.29 mm (95% confidence interval [CI] 0.19-0.39) and 0.32 mm (CI 0.21-0.43) at 2 years. The pooled retroversion at 3 months was 0.51° (CI 0.33-0.70) and 0.70° (CI 0.48-0.93) at 2 years. Hydroxyapatite-coated stems showed the least migration (subsidence 0.26 mm; CI 0.13-0.40; retroversion 0.51°; CI 0.22-0.80) among different coating types. The anterior approach showed more migration (subsidence 1.04 mm, CI 0.53-1.55; retroversion 1.52°, CI 1.08-1.95) than other surgical approaches.

conclusionOur study shows that most subsidence and retroversion of uncemented femoral stems occurs during the first 3 months. Stabilization of subsidence occurred after 3 months, and retroversion stabilized after 2 years. Migration patterns differ based on stem type, coating, surgical approach, the time period when inclusion started, and timing of baseline measurement.

Indexed as

Arthroplasty, Replacement, HipForeign-Body MigrationHip ProsthesisProsthesis FailureCohort StudiesHumansProsthesis DesignRadiostereometric Analysis

Identifiers

PMID41989304
PMCPMC13085547

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.