Evidence map›Paper›PMID 41989285›Full record

ArticleeLife2026

Global transcription factors analyses reveal hierarchy and synergism of regulatory networks and master virulence regulators in

Jiadai Huang, Yue Sun, Fang Chen, Shumin Li, Xiangkai You, Liangliang Han, Jingwei Li, Zhe He, Canfeng Hua, Chunyan Yao and 4 more

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jiadai Huang *Department of Biomedical Sciences, City University of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0000-0002-4104-6836
Yue Sun *Department of Biomedical Sciences, City University of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0009-0008-2843-0017
Fang Chen *Department of Biomedical Sciences, City University of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0000-0002-2154-4440
Shumin LiDepartment of Computer Science, The University of Hong Kong, Hong Kong, China.
Xiangkai YouDepartment of Biomedical Sciences, City University of Hong Kong, Hong Kong, China.
Liangliang HanDepartment of Biomedical Sciences, City University of Hong Kong, Hong Kong, China.
Jingwei LiDepartment of Biomedical Sciences, City University of Hong Kong, Hong Kong, China.
Zhe HeDepartment of Biomedical Sciences, City University of Hong Kong, Hong Kong, China.
Canfeng HuaDepartment of Biomedical Sciences, City University of Hong Kong, Hong Kong, China.
Chunyan YaoDepartment of Biomedical Sciences, City University of Hong Kong, Hong Kong, China.
Tianmin LiDepartment of Biomedical Sciences, City University of Hong Kong, Hong Kong, China.
Beifang LuDepartment of Biomedical Sciences, City University of Hong Kong, Hong Kong, China.
Yung-Fu ChangDepartment of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, United States.ORCID https://orcid.org/0000-0001-8902-3089
Xin DengDepartment of Biomedical Sciences, City University of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0000-0003-1580-0089

Funding

General Research Funds of Hong Kong 11101722General Research Funds of Hong Kong 11102223General Research Funds of Hong Kong 11103221Guangdong Major Project of Basic and Applied Basic Research 2020B0301030005Health and Medical Research Fund 20190942Hong Kong Research Grants Council Collaborative Research Fund CRF C7033-20GNational Natural Science Foundation of China 32172358Shenzhen Science and Technology Fund JCYJ20210324134000002Theme-based Research Scheme T11-104/22-R
6 · The paper itself

Abstract

The transcription factor (TF) regulatory network in

Indexed as

Bacterial ProteinsGene Expression Regulation, BacterialGene Regulatory NetworksPseudomonas aeruginosaTranscription FactorsVirulence FactorsBinding SitesChromatin Immunoprecipitation SequencingPromoter Regions, GeneticVirulenceBacterial ProteinsTranscription FactorsVirulence FactorsChIP-seqinfectious diseasemicrobiologyP. aeruginosatranscription factorsvirulence

Identifiers

PMID41989285
PMCPMC13086498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.