Evidence map›Paper›PMID 41989268›Full record

ArticleActa ophthalmologica2026

The Tutopatch® assisted surgery for complex strabismus study: TASCS-study.

Ires A W Verhees, Hinke Marijke Jellema, Anne-Marie E L Langenhorst, B Jeroen Klevering, Laurentius J van Rijn, Annabel L W Groot

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Article in Acta ophthalmologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ires A W VerheesDepartment of Ophthalmology, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID https://orcid.org/0009-0000-0975-6742
Hinke Marijke JellemaDepartment of Ophthalmology, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-0435-096X
Anne-Marie E L LangenhorstDepartment of Ophthalmology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
B Jeroen KleveringDepartment of Ophthalmology, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0002-3062-6544
Laurentius J van RijnDepartment of Ophthalmology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0003-3923-478X
Annabel L W GrootDepartment of Ophthalmology, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0001-7777-1522

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the efficacy of tendon elongation using bovine pericardium (Tutopatch®) in complex strabismus surgeries, with a specific focus on longer follow-up of postoperative outcomes and patient satisfaction.

methodsIn this pre-post cohort study, the records of all patients who underwent tendon elongation strabismus surgery with Tutopatch® at Radboudumc and Amsterdam UMC were retrospectively reviewed. Eligible patients were invited for a single prospective follow-up visit to assess long-term outcomes. Strabismus angle (success defined as ≤5.71° of orthotropia) and duction limitations (converted to a pseudo-quantitative scale ranging from 0 to 5) were evaluated preoperatively, 1 week postoperatively, 3 months postoperatively and at longer intervals where possible. Patient satisfaction was measured on a Visual Analogue Scale at the prospective follow-up.

resultsSixty-nine participants (mean age 41.3 ± 18.4 years) were included. Fifty-one patients had childhood onset and eighteen patients had acquired onset of strabismus. Tutopatch® was predominantly used to correct the horizontal deviation. Long-term follow-up data (>17.4 weeks) were available for 49 patients (71%), with a median follow-up of 124 weeks (range 19.9-431 weeks) and surgical success was achieved in 73% (near) and 60% (distance). Duction limitations significantly increased postoperatively, especially in exodeviations, but improved over time and seemed to have minimal impact on ocular alignment in primary position. Patient satisfaction was very high (median VAS 9.0), with only weak-to-moderate correlation with ocular alignment.

conclusionTutopatch® is a viable surgical option for tendon elongation in complex strabismus cases with favorable long-term ocular alignment, mild duction limitation and high patient satisfaction.

Indexed as

Eye MovementsOculomotor MusclesOphthalmologic Surgical ProceduresPericardiumStrabismusTendonsVision, BinocularAdolescentAdultAgedAnimalsCattleChildChild, PreschoolFemaleFollow-Up Studiesbovine pericardiumduction limitationsextraocular muscle tendon elongationocular alignmentstrabismus surgeryTutopatch®

Identifiers

PMID41989268

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.