Evidence map›Paper›PMID 41988963›Full record

Observational studyJournal of the American Heart Association2026

Seasonality of Selected Cardiovascular Disorders in Austria: A Retrospective Observational Study Between 2009 and 2023.

Maria Elisabeth Leinweber, Amun Georg Hofmann

Abstract readObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Maria Elisabeth Leinweber *FIFOS-Forum for Integrative Research & Systems Biology Vienna Austria.ORCID 0009-0003-8439-8860
Amun Georg Hofmann *FIFOS-Forum for Integrative Research & Systems Biology Vienna Austria.ORCID 0000-0001-8264-7796

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronoepidemiological patterns in general and seasonality in specific have been investigated for a multitude of pathologies. Although cardiovascular events such as myocardial infarction and stroke are well researched, evidence on other vascular segments and events remains comparably small.

methodsA retrospective observational study analyzed hospital admission data from 2009 to 2023 for pulmonary embolism (PE), aortic dissection (AD), deep vein thrombosis (DVT), acute limb ischemia, and ruptured abdominal aortic aneurysm.

resultsSeasonal variation was most pronounced for PE and AD, with winter peaks and summer troughs (PE 21.5 versus 17.6 admissions/day, -18.2%; AD 2.53 versus 2.06 admissions/day, -18.6%). DVT showed similar fluctuations (peak-to-trough ratio 1.19), whereas acute limb ischemia and ruptured abdominal aortic aneurysm demonstrated smaller absolute variation. Marked weekend effects were observed, with reductions of 65.5% (DVT), 52.5% (PE), 55.2% (acute limb ischemia), and 39.2% (AD); ruptured abdominal aortic aneurysm varied by 15.0%. Although admissions on daylight saving time days were lower than the annual average (eg, PE -42.9%, DVT -52.2%), differences compared with other Sundays were small (mostly <10%), and post-daylight saving time weeks differed by <6% from control weeks.

conclusionThis 15-year analysis confirms significant seasonal and weekend effects in vascular emergency admissions, particularly for PE, AD, and DVT. Regional differences in season manifestation and health care access limit generalizability, necessitating context-specific research into underlying mechanisms, including air pollution, health care system characteristics, and behavioral factors, to inform targeted interventions.

Indexed as

Cardiovascular DiseasesSeasonsAortic Aneurysm, AbdominalAortic RuptureAustriaFemaleHumansIschemiaMalePatient AdmissionPulmonary EmbolismRetrospective StudiesTime FactorsVenous Thrombosisacute limb ischemiaaortic aneurysmaortic dissectionchronobiologydeep venous thrombosispulmonary aneurysmseasonality

Identifiers

PMID41988963
PMCPMC13279248

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.