Evidence map›Paper›PMID 41988907›Full record

ArticleBioMed research international2026

Synthesis, Biological Evaluation, and Molecular Docking of Tellurium-Containing Benzothiazole Derivatives as Enzyme Inhibitors of DNA Gyrase and Dihydrofolate Reductase.

Olha Haleha, Valeriy Pantyo, Nataliya Korol, Elvira Danko, Mykhailo Onysko

Abstract read
In one paragraph

Article in BioMed research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Olha HalehaDepartment of Organic Chemistry, Educational and Research Institute of Chemistry and Ecology, Uzhhorod National University, Uzhhorod, Ukraine.ORCID https://orcid.org/0009-0005-9585-0335
Valeriy PantyoDepartment of Microbiology, Virology, Epidemiology With the Course of Infectious Diseases, Uzhhorod National University, Uzhhorod, Ukraine.ORCID https://orcid.org/0000-0002-0207-3372
Nataliya KorolDepartment of Organic Chemistry, Educational and Research Institute of Chemistry and Ecology, Uzhhorod National University, Uzhhorod, Ukraine.ORCID https://orcid.org/0000-0001-7155-1676
Elvira DankoDepartment of Restorative Dentistry, Educational and Scientific Institute of Dentistry and Laboratory Medicine, Uzhhorod National University, Uzhhorod, Ukraine.ORCID https://orcid.org/0000-0002-3997-9311
Mykhailo OnyskoDepartment of Organic Chemistry, Educational and Research Institute of Chemistry and Ecology, Uzhhorod National University, Uzhhorod, Ukraine.ORCID https://orcid.org/0000-0001-6121-828X

Funding

National Research Foundation of Ukraine 2023.03/0176
6 · The paper itself

Abstract

Tellurium-containing heterocycles represent an emerging class of organochalcogen compounds with notable redox properties and antimicrobial potential. Incorporation of tellurium into sulfur- and nitrogen-containing frameworks can enhance biological activity through increased polarizability and favorable noncovalent interactions. In this study, a series of novel alkenyl and alkynyl thio-derivatives of 2-mercaptobenzothiazole were synthesized via electrophilic heterocyclization with tellurium tetrahalides and evaluated for antibacterial and antibiofilm activity. The resulting benzothiazolium tellurate derivatives were characterized by IR and

Indexed as

BenzothiazolesDNA GyraseFolic Acid AntagonistsTelluriumTetrahydrofolate DehydrogenaseTopoisomerase II InhibitorsAnti-Bacterial AgentsBiofilmsEscherichia coliMicrobial Sensitivity TestsMolecular Docking SimulationStaphylococcus aureusAnti-Bacterial AgentsbenzothiazoleBenzothiazolesDNA GyraseFolic Acid AntagonistsTelluriumTetrahydrofolate DehydrogenaseTopoisomerase II Inhibitors

Identifiers

PMID41988907
PMCPMC13084523

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.