SynthesisBioMed research international2026
Genicular Nerve Radiofrequency Ablation for Persistent Postsurgical Pain After Total Knee Arthroplasty: A Systematic Review of Clinical Effectiveness and Safety.
Synthesis in BioMed research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Genicular Nerve Radiofrequency Ablation for Persistent Postsurgical Pain After Total Knee Arthroplasty: A Systematic Review of Clinical Effectiveness and Safety.BioMed research international · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTotal knee arthroplasty is an effective and established surgical treatment of knee osteoarthritis. However, patients report significant perioperative pain and persistent postsurgical pain, which in turn affect the recovery of the patients. Current treatment options include multimodal analgesia. Lately, RFA has been suggested as a procedure for post-TKA pain management. This systematic review is aimed at critically evaluating the current evidence on the effectiveness and safety of RFA of the genicular nerve as a persistent postoperative pain management in patients after TKA.
methodsThis systematic review focused on RCTs and cohort studies. The search of the literature was done on several databases.
resultsTen studies, including one RCT and nine retrospective cohort studies with a total of 211 patients, were included. Studies included different RFA techniques and imaging modalities. All studies reported improvement in outcome measures after the procedure according to different scales. The bias assessment revealed moderate-to-high risk. The statistical analysis was not done due to heterogeneity of the results.
conclusionGNRFA is a promising modality, which reports improvement in outcome measures and absence of adverse effects. It is promising for selected patients but requires RCTs for routine use.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.