Evidence map›Paper›PMID 41988803›Full record

ArticleThe British journal of clinical psychology2026

Do schema modes predict outcome of cognitive behavioural therapy in patients with obsessive-compulsive disorder and anxiety disorders?

Manon Peeters, Boris van Passel, Nancy Peeters, Julie Krans

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Article in The British journal of clinical psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Manon PeetersPro Persona Overwaal Centre for Anxiety, OCD and PTSD, Nijmegen, The Netherlands.
Boris van PasselPro Persona Overwaal Centre for Anxiety, OCD and PTSD, Nijmegen, The Netherlands.
Nancy PeetersPro Persona Overwaal Centre for Anxiety, OCD and PTSD, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0002-2988-9478
Julie KransPro Persona Overwaal Centre for Anxiety, OCD and PTSD, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0001-8015-9844

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCognitive behavioural therapy (CBT) is the psychological treatment of choice for patients with obsessive-compulsive disorder (OCD) or an anxiety disorder. However, a substantial group (30-40%) does not profit sufficiently. Predictors of outcome inform us about how to adapt interventions for this group. Specifically, schema modes might affect CBT outcome; yet, research into the relation between schema modes and CBT outcome for anxiety disorders and OCD is very limited. In this study, it was investigated whether adaptive and maladaptive schema modes predict CBT outcome controlling for symptom levels at the start of treatment.

methodsPre-treatment maladaptive and adaptive schema modes and pre- and post-treatment psychological distress were assessed in 100 patients (60 women and 40 men with a mean age of 32.49 years) diagnosed with OCD (n = 56) or an anxiety disorder (n = 44) receiving CBT. Regression analyses were conducted to assess the unique predictive value of adaptive and maladaptive schema modes in addition to pre-treatment levels of psychological distress.

resultsPre-treatment maladaptive modes (specifically maladaptive child modes) significantly predicted psychological distress after CBT with small effect sizes. Higher pre-treatment adaptive modes were associated with better CBT response, although this effect was not robust.

conclusionsGiven the small effect size, our study does not yield strong evidence that schema modes influence CBT outcome for patients with OCD or anxiety disorders. Given that this is the first study testing this effect, our findings need to be replicated, preferably in disorder-specific samples.

Indexed as

Adaptation, PsychologicalAnxiety DisordersCognitive Behavioral TherapyObsessive-Compulsive DisorderOutcome Assessment, Health CareAdultFemaleHumansMaleMiddle AgedTreatment OutcomeYoung Adultanxiety disordersCBTnon‐responseOCDschema modesschema therapy

Identifiers

PMID41988803
PMCPMC13655967

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.