Trial reportFrontiers in public health2026
Effects of a culturally tailored intervention on medication adherence in Chinese and Vietnamese Americans with hepatitis B: a randomized controlled trial.
Trial report in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04082338 (Long-Term Adherence To Monitoring/Treatment In Underserved Asian Americans With Chronic HBV), which is not on this map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Long-Term Adherence To Monitoring/Treatment In Underserved Asian Americans With Chronic HBV
Who cites it
2 citing papers in PubMed.
- Longitudinal Adherence Trajectories of First-Line Nucleotide Analogues among US Older Adults with Chronic Hepatitis B.Drugs & aging · 2026Article
- Associations of social support and disease-specific quality of life with self-management among patients with chronic hepatitis B: a multicenter cross-sectional study.Frontiers in public health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Introduction: Asian Americans are disproportionately affected by chronic hepatitis B (CHB), which is caused by infection with hepatitis B virus (HBV). While adherence to antiviral medication is an effective practical approach to managing CHB and preventing liver cancer, medication adherence rates among Chinese and Vietnamese Americans with CHB, two vulnerable yet understudied populations, remain largely unknown. Methods: We designed and implemented a randomized controlled clinical trial to investigate the potential improvement of long-term adherence to HBV medication in Asian American populations. Eligible Asian American HBV patients were recruited from the Greater Philadelphia and New York City. HBV medication adherence was assessed using the 8-Item Morisky Medication Adherence Scale. We conducted ordinary least squares (OLS) regression to examine the intervention effects on medication adherence among 129 Chinese and Vietnamese Americans taking CHB medication. Results: Among 129 participants (91 Chinese and 38 Vietnamese), about three-quarters (74.4%) reported limited English proficiency. Almost one out of 10 (9.3%) did not have any health insurance. OLS regression results indicated that the intervention had a significant impact on improving medication adherence at 12-month follow-up assessment (coefficient = 0.56, Discussion: The findings show that a community-based culturally appropriate intervention significantly improved adherence to medication among Chinese and Vietnamese Americans with CHB in a 12-month period. Providing mental health support to CHB patients in this population may play an important role in improving medication adherence. Clinical trial registration: [https://clinicaltrials.gov/study], identifier [NCT04082338].
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