Evidence map›Paper›PMID 41988487›Full record

ArticleFrontiers in neurology

Impact of collateral status on functional outcomes in acute cardioembolic stroke after successful endovascular thrombectomy.

Jun Chen, Fanghui Li, Mingjun Pu, Zhonglun Chen, Zhaokun Li, Xinyu Zou, Jiacai Zuo, Ying Cao, Ling Yang, Min Luo and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jun Chen *Department of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Fanghui Li *Department of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Mingjun PuMianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, China.
Zhonglun ChenDepartment of Neurology, Mianyang Third People's Hospital, Mianyang, China.
Zhaokun LiMianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, China.
Xinyu ZouMianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, China.
Jiacai ZuoMianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, China.
Ying CaoDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Ling YangMianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, China.
Min LuoMianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, China.
Yufeng TangMianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, China.
Rui ZengDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Collateral circulation sustains the ischemic penumbra during acute large vessel occlusion (LVO). However, its prognostic significance in cardioembolic stroke (CS) patients following successful endovascular thrombectomy (EVT) remains unclear. We investigated whether collateral status influences functional outcomes in acute CS patients achieving successful recanalization [modified Thrombolysis in Cerebral Infarction (mTICI) grade ≥2b]. Methods: We retrospectively analyzed consecutive CS patients achieving successful recanalization with EVT. Collateral status was assessed using the American Society of Interventional and Therapeutic Neuroradiology/Society of Interventional Radiology (ASITN/SIR) grading system on digital subtraction angiography (DSA). The primary outcome was functional independence [modified Rankin Scale (mRS) 0-2] at 3 months. Secondary outcomes included excellent outcome (mRS 0-1) at 3 months, in-hospital and 3-month mortality, and PH (parenchymal hematoma type 1c or 2) within 72 h. Multivariable logistic regression and subgroup analyses were performed to identify independent associations. Results: Among 354 patients, 211 (59.6%) had good collaterals (ASITN/SIR 2-4) and 143 (40.4%) had poor collaterals (ASITN/SIR 0-1). After adjustment for confounders, good collateral status independently predicted functional independence [adjusted odds ratio (aOR), 2.07; 95% CI, 1.13-3.83; Conclusion: In CS patients achieving successful recanalization, good collateral status is independently associated with improved functional independence and excellent outcome, reduced PH rates within 72 h, and lower in-hospital mortality and 3-month mortality. Collateral assessment may enhance prognostic stratification, particularly in patients with lower baseline ASPECTS.

Indexed as

cardioembolic strokecollateral statusendovascular thrombectomyfunctional outcomelarge vessel occlusion

Identifiers

PMID41988487
PMCPMC13076178

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