Evidence map›Paper›PMID 41988462›Full record

ArticleInternational journal of women's health2026

Maternal and Fetal Outcomes in Pregnant Women with Acute Leukemia.

Fangfang Jian, Li Chen, Yan Liu, Chenmin Yang

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Article in International journal of women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Fangfang Jian *Department of Obstetrics and Gynecology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People's Republic of China.
Li Chen *Department of Hematology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People's Republic of China.
Yan LiuDepartment of Obstetrics and Gynecology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People's Republic of China.
Chenmin YangDepartment of Obstetrics and Gynecology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People's Republic of China.ORCID 0000-0003-2693-4306

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Acute leukemia (AL) during pregnancy is a rare condition with limited evidence-based information available on the management. The study aims to analyze the pregnancy and fetal outcomes of pregnant women with acute leukemia diagnosed during pregnancy. Methods: In this retrospective study, 18 pregnant women who were diagnosed with AL during pregnancy from January 2013 to January 2024 were reviewed. Results: Of these patients, 6 delivered before chemotherapy while 12 received chemotherapy after induced abortion. Six fetus were born through spontaneous delivery or cesarean section, and one died 3 days after birth. Fourteen patients (77.8%) were found to have decreased platelets by full blood count test. The delivery group had a longer gestational age, longer time from pregnancy termination to chemotherapy compared to the abortion group. The median age of the rest 5 newborns was 32 months. Five newborns were healthy without any deformities or developmental issues. With a median follow-up of 3 years, the overall survival (OS) rates for 18 patients with acute leukemia were estimated at 88.2%. Patients in the delivery group had a significantly lower OS rate compared to those in abortion group. Overall, starting chemotherapy as soon as possible can improve OS rates for pregnant women with AL. Conclusion: Collectively, we suggest that for pregnant patients diagnosed in early or late stages of pregnancy (after 30 weeks), opting for termination of pregnancy before starting chemotherapy could lead to better outcomes for the mothers.

Indexed as

acute leukemiafetal outcomesmaternal outcomespregnancy

Identifiers

PMID41988462
PMCPMC13077843

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