ArticleHealth science reports2026
Comparison of the Efficacy of Q-Switched Versus Long-Pulsed Fractional 1064 nm Nd:YAG Laser in the Treatment of Active Facial Acne: A Pilot, Double-Blind, Randomized, Controlled, Split-Face Study.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Comparison of the efficacy and safety of intense pulsed light (IPL), pulsed dye laser (PDL), and Q-switched neodymium-doped yttrium aluminum garnet (Nd: YAG) laser in the treatment of moderate to severe inflammatory acne: a three-arm randomized controlled clinical trial.Lasers in medical science · 2026Trial
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Authors and funding
5 authors.
Funding
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Abstract
Background and Aims: There are different treatment options for acne including topicals, systemic, hormonal, intralesional, and laser treatments. Fractional Nd: YAG 1064 nm laser has been used to treat acne scars and there are also reports on its use in active acne. In this pilot, split-face, randomized trial conducted as an adjunct to standard care, the aim was to compare effects of long-pulse (LP) with Quality-switched (QS) Nd:YAG laser on active acne. Methods: This is a double-blind, randomized, controlled, split-face study comparing LP versus QS Nd: YAG laser for treating active acne in 20 participants (age range, 18-50 years). Patients had 3 sessions of treatment with 3-week intervals, with a final follow-up 4 weeks later. Assessments were performed using the modified Leeds revised acne grading system, physician global assessment and patient global satisfaction. All participants received daily oral azithromycin as standardized background therapy; lasers were evaluated as adjunctive treatments. Results: Both laser modes decreased means of modified Leeds scores at final follow-up. The percentage change was significantly higher in QS compared to LP group (50% vs. 32%, paired comparison Conclusion: As adjuncts to daily azithromycin, both LP and QS 1064 nm Nd:YAG lasers showed reductions in acne severity; QS demonstrated a modest within-subject advantage. Given the small sample and adjunctive systemic therapy, findings are preliminary and hypothesis-generating.
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