ArticleJournal of thoracic disease2026
Diaphragm assessment by multimodal ultrasound imaging in patients with interstitial lung disease: a prospective observational study.
Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The dyspnea experienced by patients with interstitial lung disease (ILD) is partly attributable to diaphragmatic dysfunction. This study aims to quantitatively evaluate diaphragmatic function in ILD patients by measuring different diaphragm ultrasound parameters, seeking to gain a more comprehensive understanding of diaphragmatic characteristics in this population. Methods: Forty-four ILD patients and 31 healthy controls were prospectively enrolled and underwent diaphragmatic ultrasound. Parameters measured included diaphragmatic thickness, excursion, and tissue Doppler imaging (TDI)-derived acceleration and velocity. Intra-operator reliability of ultrasound measurements was validated using intraclass correlation coefficient (ICC) and Bland-Altman analysis, and multivariate regression analysis was performed to adjust for confounding factors. Correlations between ultrasound parameters and clinical/pulmonary function indices were analyzed. Results: Compared with controls, ILD patients had greater diaphragmatic thickness during quiet breathing (QB) (end-expiration 0.21 Conclusions: Multimodal ultrasound allows for the evaluation of diaphragmatic function in patients with ILD. ILD patients exhibit diaphragmatic structural and functional abnormalities (thickening, reduced contractility/excursion, increased activation) that correlate with clinical indicators of disease severity. As a non-invasive tool, diaphragmatic ultrasound parameters may provide a reference for assessing respiratory function-related outcomes in ILD patients, though direct evidence linking these parameters to respiratory function is lacking. Given the moderate sample size and cross-sectional design of this study, the clinical utility of these ultrasound parameters requires validation in larger, prospective cohorts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.