Evidence map›Paper›PMID 41988316›Full record

ArticleJournal of thoracic disease2026

Single-sterilization modified-position robotic-assisted McKeown esophagectomy versus minimally invasive approach after neoadjuvant chemoimmunotherapy for locally advanced esophageal squamous cell carcinoma.

Hailiang Cai, Guoqing Liao, Weijie Zhan, Yuhang Zhang, Lintong Yao, Liyu Cai, Weihuan Lin, Shaowei Wu, Jens-C Rueckert, Luyu Huang and 1 more

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hailiang Cai *School of Medicine South China University of Technology, Guangzhou, China.
Guoqing Liao *Department of Thoracic Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Weijie Zhan *School of Medicine South China University of Technology, Guangzhou, China.
Yuhang ZhangDepartment of Thoracic Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0009-0000-9295-4861
Lintong YaoDepartment of Thoracic Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0009-0008-0382-5047
Liyu CaiShenShan Hospital, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Shanwei, China.
Weihuan LinSchool of Medicine South China University of Technology, Guangzhou, China.
Shaowei WuDepartment of Thoracic Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0002-0265-9787
Jens-C RueckertDepartment of Surgery, Competence Center of Thoracic Surgery, Charite-Universitatsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-3940-4630
Luyu HuangDepartment of Thoracic Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0002-5791-4781
Haiyu ZhouSchool of Medicine South China University of Technology, Guangzhou, China.ORCID https://orcid.org/0000-0002-3328-6792

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Surgical resection remains a key component of multimodal therapy for patients with resectable or locally advanced esophageal squamous cell carcinoma (ESCC) after neoadjuvant chemoimmunotherapy (nCIT). This study compared the safety and efficacy of single-sterilization modified-position robotic-assisted esophagectomy (SM-RAE) with conventional minimally invasive esophagectomy (MIE), focusing on perioperative outcomes, composite adverse events, electronic patient-reported outcomes (ePROs), and short-term oncologic results. Methods: This single-center retrospective study included 137 ESCC patients who underwent McKeown esophagectomy after nCIT between January 2022 and December 2024. Of them, 36 received SM-RAE and 101 received MIE. Baseline characteristics, perioperative indicators, composite adverse events (operative time ≥330 min, intraoperative blood loss ≥400 mL, conversion to open, non-R0 resection, or Clavien-Dindo grade ≥ III complications), ePROs (pain, cough, distress, dysphagia, and dyspnea), and short-term survival outcomes were analyzed. Propensity score matching (PSM) was applied to balance baseline variables, and comparisons were repeated after matching. Results: Compared with MIE, SM-RAE resulted in shorter operative time (270 Conclusions: SM-RAE is a safe, effective, and feasible surgical option for ESCC patients after nCIT. For selected patients with locally advanced disease, SM-RAE offers a non-inferior alternative to standard MIE, with advantages in perioperative efficiency, RLN lymphadenectomy, and patient-reported recovery.

Indexed as

Esophageal squamous cell carcinoma (ESCC)minimally invasive esophagectomy (MIE)neoadjuvant chemoimmunotherapy (nCIT)patient-reported outcomes (PROs)robotic-assisted esophagectomy (RAE)

Identifiers

PMID41988316
PMCPMC13077432

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.