ArticleJournal of thoracic disease2026
Short-term outcomes of Perceval sutureless valve replacement in patients with type 0 bicuspid aortic valve.
Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The Perceval sutureless aortic valve offers favorable hemodynamics and reduced operative times in surgical aortic valve replacement (AVR). However, its use in patients with type 0 bicuspid aortic valve (BAV), a condition characterized by annular asymmetry and absence of a raphe, remains controversial, and evidence for this specific anatomical subtype remains limited. This study evaluated the short-term outcomes of Perceval valve implantation in patients with type 0 BAV. Methods: This single-center, retrospective cohort study included 11 consecutive patients with type 0 BAV who underwent Perceval sutureless AVR between June 2022 and February 2025. All procedures were performed via median sternotomy by a single experienced surgeon. Perioperative, echocardiographic, and clinical outcomes were obtained from institutional databases. Follow-up was conducted through structured telephone interviews. Results: All procedures were completed successfully without intraoperative complications. The mean annular diameter was 22.7±1.6 mm, and the mean eccentricity index was 0.2±0.1. Cardiopulmonary bypass and cross-clamp times were 79.6±19.1 and 55.0±16.4 minutes, respectively. No patient experienced paravalvular leakage (PVL), atrioventricular block requiring permanent pacing, valve migration, stroke, or in-hospital mortality. Discharge echocardiography indicated preserved ventricular function and favorable hemodynamics, with a mean gradient of 12.8±1.9 mmHg. Over a median follow-up of 11 months (range, 2-13 months), no valve-related complications, reinterventions, or late deaths occurred. Conclusions: The findings from this study indicate that the Perceval sutureless valve can be safely and effectively implanted in selected patients with type 0 BAV, including those with a small aortic annulus. With proper preoperative assessment, favorable short-term outcomes can be consistently achieved.
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