ReviewJournal of thoracic disease2026
Optimizing perioperative care in esophagectomy: a narrative review.
Review in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Development and internal validation of an interpretable machine learning prognostic prediction model for postoperative delirium after esophagectomy.Journal of thoracic disease · 2026Article
- Biological and Targeted Therapies in the Multidisciplinary Management of Gastrointestinal Cancers.Cancers · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Objective: Perioperative management of esophageal cancer surgery is continuously evolving. Advances in patient preparation, surgical techniques, and the implementation of enhanced recovery after surgery (ERAS) protocols have collectively improved postoperative outcomes and recovery. Minimally invasive esophagectomy has been widely adopted due to its association with reduced surgical trauma, less blood loss, shorter hospital stay, and, in some studies, lower complication rates. Despite these advances, esophagectomy remains a high-risk procedure with substantial morbidity, underscoring the need for continued optimization of perioperative care. This review focuses on recent developments in perioperative care and their impact on outcomes in esophageal cancer surgery. Methods: This narrative review provides an overview of the literature on perioperative optimization in esophageal cancer surgery, with emphasis on developments from the past several years, and is structured around key domains including prehabilitation, surgical techniques, ERAS protocols, and emerging experimental strategies. Key Content and Findings: Structured prehabilitation programs combining physical training, psychological support, and nutritional optimization have demonstrated complementary benefits in enhancing functional reserve and surgical tolerance. Current clinical practice increasingly focuses on technical refinement of minimally invasive esophagectomy, with growing adoption of robot-assisted techniques to enhance surgical precision and postoperative outcomes. Within ERAS, postoperative nutritional management is one of the least consistently implemented components, although direct oral feeding after minimally invasive esophagectomy has been shown to be safe and feasible and may enhance recovery and even long-term outcomes. In parallel with these advances, experimental strategies have been explored to further attenuate perioperative inflammation. Neuromodulation of the sympathetic nervous system has shown potential to modulate the postoperative immune response and holds promise for further improving postoperative outcomes. Conclusions: Perioperative care for esophagectomy has evolved towards a multimodal and patient-centered approach. Optimization of prehabilitation, minimally invasive (including robotic) techniques and ERAS-based perioperative care may further improve postoperative outcomes. Neuromodulation may represent a promising adjunct but requires further clinical validation. Continued refinement of perioperative pathways may contribute not only to faster recovery, but also to improved long-term outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.