ArticleJournal of thoracic disease2026
Global, regional, and temporal trends in aortic aneurysm burden, 1990-2021: insights from the Global Burden of Disease study.
Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Aortic aneurysm (AA) is a serious cardiovascular condition with high mortality. This study evaluated the global burden, temporal trends, projections, and regional disparities of AA, focusing on variations across Socio-Demographic Index (SDI) regions. Methods: Based on publicly available Global Burden of Disease (GBD) 2021 estimates, we analyzed the global and regional burden of AA from 1990 to 2021. Pearson's correlation assessed the association between age-standardized mortality rates (ASMR) and age-standardized disability-adjusted life years (ASDR) for AA and 2021 SDI values. A Bayesian age-period-cohort (BAPC) model projected deaths and disability-adjusted life years (DALYs) to 2030. An age-period-cohort (APC) model assessed effects across SDI regions. A preliminary evaluation of risk factors was also conducted. Results: From 1990 to 2021, global absolute AA-related deaths and DALYs increased by 74.1% and 64.9%, respectively, with further increases projected by 2030. In contrast, ASMR and ASDR declined and are projected to continue decreasing. At the global level, ASMR and ASDR demonstrated a modest but significant positive correlation with SDI values (P<0.001). Stratified analyses revealed distinct regional patterns. Notably, period and cohort effects in high and high-middle SDI regions were opposite to those in middle, low-middle, and low SDI regions. Conclusions: Tailored intervention strategies are essential to address the heterogeneous burden of AA across SDI regions. While sustained attention is needed in high and high-middle SDI regions, greater vigilance is required in low-middle SDI regions, where the potential burden remains substantial.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.