ArticleJournal of thoracic disease2026
Thoracic paravertebral block with liposomal bupivacaine versus ropivacaine for postoperative analgesia in thoracic surgery: a randomized controlled study.
Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Liposomal bupivacaine in thoracic surgery: a comprehensive review of current evidence and clinical implications.Frontiers in medicine · 2026Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Paravertebral block is a highly effective regional analgesic technique for thoracic surgery. Liposomal bupivacaine (LB) significantly extends the duration of analgesia. However, the efficacy of LB for thoracic paravertebral block (TPVB) in patients undergoing video-assisted thoracic surgery (VATS) remains unclear. This trial aimed to evaluate the analgesic efficacy of TPVB with LB following VATS. Methods: In this prospective, randomized controlled trial, patients scheduled for VATS were randomly assigned (1:1) to receive either LB or ropivacaine. All patients received a standardized multimodal analgesic regimen, which included a preoperative ultrasound-guided TPVB and patient-controlled intravenous analgesia. The primary outcome was the Numerical Rating Scale (NRS) score for pain during coughing at 24 hours postoperatively. Results: Among 100 patients undergoing VATS, paravertebral analgesia with LB provided superior pain control compared to ropivacaine. At 24 hours postoperatively, the LB group demonstrated significantly lower median cough NRS pain scores [median: 4 (IQR, 3, 6) Conclusions: Preoperative administration of LB for TPVB effectively reduced postoperative pain in patients undergoing VATS and was associated with a lower incidence of vomiting and dizziness. Trial Registration: Chinese Clinical Trial Registry, ChiCTR2400087560 (registered on July 30, 2024).
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