Evidence map›Paper›PMID 41988231›Full record

ArticleJournal of experimental orthopaedics2026

Post-operative septic arthritis after anterior cruciate ligament reconstruction results in higher osteoarthritis severity and deficit of range of motion: A matched control analysis with a minimum 8-year follow-up.

Sebastian Imach, Steffen T Ubl, Carolin Flieser, Julius Stüber, Sven Shafizadeh, Arasch Wafaisade, Jan-Hendrik Naendrup, Daniel Guenther, Bertil Bouillon, Thomas R Pfeiffer

Abstract read
In one paragraph

Article in Journal of experimental orthopaedics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sebastian ImachDepartment of Orthopaedic Surgery, Trauma Surgery and Sports Medicine, Cologne Merheim Medical Center Witten/Herdecke University Cologne Germany.ORCID https://orcid.org/0000-0002-8879-9050
Steffen T UblDepartment of Orthopaedic Surgery, Trauma Surgery and Sports Medicine, Cologne Merheim Medical Center Witten/Herdecke University Cologne Germany.ORCID https://orcid.org/0000-0002-9088-334X
Carolin FlieserDepartment of Orthopaedic Surgery, Trauma Surgery and Sports Medicine, Cologne Merheim Medical Center Witten/Herdecke University Cologne Germany.
Julius StüberDepartment of Orthopaedic Surgery, Trauma Surgery and Sports Medicine, Cologne Merheim Medical Center Witten/Herdecke University Cologne Germany.
Sven ShafizadehDepartment of Orthopedic Surgery and Sports Traumatology Sana Medical Centre Cologne Germany.ORCID https://orcid.org/0009-0006-2474-3062
Arasch WafaisadeDepartment of Orthopaedic Surgery, Trauma Surgery and Sports Medicine, Cologne Merheim Medical Center Witten/Herdecke University Cologne Germany.ORCID https://orcid.org/0000-0001-6265-9802
Jan-Hendrik NaendrupDepartment of Orthopaedic Surgery, Trauma Surgery and Sports Medicine, Cologne Merheim Medical Center Witten/Herdecke University Cologne Germany.ORCID https://orcid.org/0000-0002-6420-7938
Daniel GuentherDepartment of Orthopaedic Surgery, Trauma Surgery and Sports Medicine, Cologne Merheim Medical Center Witten/Herdecke University Cologne Germany.ORCID https://orcid.org/0000-0002-3397-5643
Bertil BouillonDepartment of Orthopaedic Surgery, Trauma Surgery and Sports Medicine, Cologne Merheim Medical Center Witten/Herdecke University Cologne Germany.ORCID https://orcid.org/0000-0002-5048-1311
Thomas R PfeifferDepartment of Orthopaedic Surgery, Trauma Surgery and Sports Medicine, Cologne Merheim Medical Center Witten/Herdecke University Cologne Germany.ORCID https://orcid.org/0000-0002-0492-6949

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Evaluating knee joint function, activity level, and osteoarthritis severity in patients at least 8 years after post-operative knee septic arthritis (SA) following anterior cruciate ligament reconstruction (ACLR). Methods: From May 2010 to January 2012, 39 patients at our institution were treated for knee SA following ACLR using graft-retaining treatment protocols. Follow-up examinations after a minimum of 8 years included clinical examination, measurement of anterior tibial translation (rolimeter), International Knee Documentation Committee Subjective Knee Form (IKDC), 12-Item Short Form Health Survey (SF-12), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Marx and Tegner scores. Osteoarthritis severity was described on radiographs using the Kellgren-Lawrence scale. Synovial fluid was aspirated from patients with persistent infection signs and evaluated using multiplex polymerase chain reaction (PCR). Based on ACLR graft, sex and preoperative Tegner score (±1), a 1:1 propensity score matched control group including patients with ACLR without knee SA signs was assembled. Results: Matching resulted in 17 patients per group. While the patient-reported outcome measures (PROMs) (IKDC, Tegner, Marx and SF-12) showed no significant differences between the groups ( Conclusions: SA after ACLR, when treated with a standardized graft-retaining protocol, results in higher OA severity, worse WOMAC scores and persistent range of motion limitations at long-term follow-up, while other PROMs and activity level remained comparable to those of non-infected cases. Level of Evidence: Level III.

Indexed as

infection after ACL reconstructionknee joint complicationslong‐term clinical outcomesosteoarthritis severityrange of motion limitation

Identifiers

PMID41988231
PMCPMC13078131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.