Evidence map›Paper›PMID 41988092›Full record

ArticleBreathe (Sheffield, England)2026

Blood eosinophil count as a biomarker for therapy guidance in COPD and asthma exacerbations.

Anuradha Nalika Godallage, Dil Afrose, Melika Valizadeh, Augusta Beech, Jens-Ulrik S Jensen, Pradeesh Sivapalan

Abstract read
In one paragraph

Article in Breathe (Sheffield, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Molecules in pulmonary medicine.Breathe (Sheffield, England) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anuradha Nalika GodallageCopenhagen Respiratory Research, Department of Medicine, Herlev and Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
Dil AfroseCopenhagen Respiratory Research, Department of Medicine, Herlev and Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.ORCID https://orcid.org/0009-0008-3513-8225
Melika ValizadehPulmonary Rehabilitation Research Center (PRRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Augusta BeechSchool of Biological Sciences, Faculty of Biology, Medicine and Health, Division of Immunology, Immunity to Infection and Respiratory Medicine, University of Manchester, Wythenshawe Hospital, Manchester, UK.ORCID https://orcid.org/0000-0002-2690-5364
Jens-Ulrik S JensenCopenhagen Respiratory Research, Department of Medicine, Herlev and Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.ORCID https://orcid.org/0000-0003-4036-0521
Pradeesh SivapalanCopenhagen Respiratory Research, Department of Medicine, Herlev and Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.ORCID https://orcid.org/0000-0002-8620-3655

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This Journal club evaluates recent evidence on the role of blood eosinophil count (BEC) as a biomarker to guide therapy in patients with acute exacerbations of COPD and asthma. The review focuses on three studies with different methodological approaches: a biomarker-directed corticosteroid trial (Bafadhel

Identifiers

PMID41988092
PMCPMC13077450

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.