Evidence map›Paper›PMID 41988075›Full record

ArticleBiophysics and physicobiology2026

Mirror life at the crossroads: Report on the symposia in Japan for discussion toward mirror life synthesis.

Kei Fujiwara, Wataru Aoki, Chikara Furusawa, Ai Hasegawa, Gosuke Hayashi, Daisuke Kiga, Koichi Mikami, Sakura Takada, Yoshihiro Shimizu

Abstract read
In one paragraph

Article in Biophysics and physicobiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kei FujiwaraDepartment of Biosciences and Informatics, Keio University, Yokohama, Kanagawa 223-8522, Japan.
Wataru AokiDepartment of Biotechnology, Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
Chikara FurusawaCenter for Biosystem Dynamics Research, RIKEN, Kobe, Hyogo 650-0047, Japan.
Ai HasegawaDepartment of Mechanical Engineering, Keio University, Yokohama, Kanagawa 223-8521, Japan.
Gosuke HayashiDepartment of Biomolecular Engineering, Nagoya University, Nagoya, Aichi 464-8603, Japan.
Daisuke KigaDepartment of Electrical Engineering and Bioscience, Waseda University, Tokyo 162-8480, Japan.
Koichi MikamiDepartment of Foreign Languages and Liberal Arts, Keio University, Yokohama, Kanagawa 223-8521, Japan.
Sakura TakadaDepartment of Biosciences and Informatics, Keio University, Yokohama, Kanagawa 223-8522, Japan.
Yoshihiro ShimizuCenter for Biosystem Dynamics Research, RIKEN, Kobe, Hyogo 650-0047, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The synthesis of mirror life, an organism composed entirely of the mirror-image counterparts of naturally occurring biomolecules, may be a topic for science fiction today but is suggested to be a reality in the future. Scientists called for strict preemptive regulation for the synthesis of mirror life due to concerns regarding biosecurity risks, such as the potential threat of mirror life to humans and non-human ecosystems. This perspective reports on the discussions held at two recent symposia in Japan, at the Japanese Society for Cell Synthesis Research (JSCSR) meeting and at the Biophysical Society of Japan (BSJ) annual meeting. Participants, including synthetic biologists, social scientists and artists, discussed the feasibility of the synthesis of mirror-image artificial self-replicating cells and the balance between the risks and benefits of this emerging technology. The discussions indicate that, while safety management is essential, a rational, evidence-based framework developed through open dialogue with society is crucial for the responsible advancement of mirror life research.

Identifiers

PMID41988075
PMCPMC13077127

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.