Evidence map›Paper›PMID 41987923›Full record

ArticleFrontiers in cardiovascular medicine2026

Prediction of hypokalemia in patients with ST-segment elevation myocardial infarction: development and validation of a model with prehospital applicability.

Qian Gu, Chao Tang, Baojun Yang, Fei Shi, Xiaosong Gu, Jing Zhu

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Qian Gu *Department of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Chao Tang *Department of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Baojun YangDepartment of Emergency, Suzhou Dushu Lake Hospital, Suzhou, China.
Fei ShiDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Xiaosong GuDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Jing ZhuDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hypokalemia is common in patients with ST-segment elevation myocardial infarction (STEMI) and significantly elevates the risk of life-threatening arrhythmias and mortality. Yet no validated prehospital prediction tool exists to identify this high-risk condition early. Objective: To develop and validate a prediction model for hypokalemia in STEMI patients using readily available clinical and electrocardiographic parameters that are fully accessible in prehospital settings, and to systematically evaluate its prehospital application potential. Methods: A retrospective observational study was conducted involving 320 STEMI patients admitted to the Second Affiliated Hospital of Soochow University between January 2023 and December 2024. Patients were categorized into hypokalemia ( Results: Five independent predictors were identified: symptom-to-door time (OR = 0.85, 95% CI: 0.78-0.94), syncope/coma (OR = 3.57, 95% CI: 1.12-11.37), atrial arrhythmia (OR = 4.18, 95% CI: 1.33-13.17), PR interval (OR = 1.01, 95% CI: 1.00-1.02), and U wave (OR = 5.20, 95% CI: 2.59-10.46). The prediction model demonstrated good discrimination with an AUC of 0.735 (95% CI: 0.680-0.791). Calibration curves and decision curve analysis confirmed satisfactory model performance and clinical usefulness. Conclusion: We developed and validated a practical nomogram for predicting hypokalemia risk in STEMI patients using five variables readily available in prehospital and emergency settings. This tool enables early risk stratification, facilitates targeted intervention in high-risk individuals, and guides early potassium supplementation. It may improve prehospital care and clinical outcomes in STEMI patients.

Indexed as

hypokalemianomogramprediction modelpre-hospital assessmentST-segment elevation myocardial infarction

Identifiers

PMID41987923
PMCPMC13077706

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