ArticleBJUI compass2026
Micro-ultrasound tissue echogenicity predicts prostate cancer grade.
Article in BJUI compass, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- From Detection to Surveillance: The Evolving Role of Micro-Ultrasound in Prostate Cancer.Diagnostics (Basel, Switzerland) · 2026Review
- Micro-ultrasound tissue echogenicity predicts prostate cancer grade.BJUI compass · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: This study aimed to evaluate the association between lesion echogenicity on micro-ultrasound (micro-US) and the presence and grade of prostate cancer. Patients and Methods: We prospectively analysed 229 prostate lesions from 181 men undergoing micro-US-guided transperineal biopsy at UCLA. Lesions were visually graded as hyperechoic, isoechoic or hypoechoic relative to the central zone, which served as an internal reference due to its consistent tissue characteristics and low malignancy risk. Biopsy targeting was confirmed by visualizing the needle tract within the lesion. The primary outcome was the detection rate of Grade Group (GG) ≥ 2 cancer across echogenicity categories. Secondary analyses included associations with PSA density and MRI-derived apparent diffusion coefficient (ADC) values, given that ADC is associated with tissue cellularity. Statistical comparisons were performed using chi-square and Kruskal-Wallis tests, with post hoc pairwise analyses where appropriate. Results: GG ≥ 2 cancer detection rates increased with decreasing echogenicity: 22% in hyperechoic, 56.2% in isoechoic and 62.4% in hypoechoic lesions ( Conclusions: Lesion hypoechogenicity on micro-US is strongly associated with higher grade prostate cancer and lower ADC values, suggesting a link to tissue cellularity. These findings support the incorporation of echogenicity as a diagnostic marker within the micro-US PRI-MUS framework, potentially enhancing the accuracy of prostate cancer risk stratification.
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