Evidence map›Paper›PMID 41987874›Full record

ArticleDevelopment & reproduction2026

Isocitrate Dehydrogenases Idh1 and Idh2 Regulate Pronephric Morphogenesis in

Hyun-Kyung Lee, Hongchan Lee, Chowon Kim, Hyun-Shik Lee

Abstract read
In one paragraph

Article in Development & reproduction, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hyun-Kyung LeeKNU G-LAMP Project Group, KNU Institute of Basic Sciences, School of Biotechnology, BK21 FOUR KNU Creative BioResearch Group, College of Natural Sciences, Kyungpook National University, Daegu 41566, Korea.ORCID https://orcid.org/0000-0003-4989-698X
Hongchan LeeKNU G-LAMP Project Group, KNU Institute of Basic Sciences, School of Biotechnology, BK21 FOUR KNU Creative BioResearch Group, College of Natural Sciences, Kyungpook National University, Daegu 41566, Korea.ORCID https://orcid.org/0000-0001-9009-209X
Chowon KimKNU G-LAMP Project Group, KNU Institute of Basic Sciences, School of Biotechnology, BK21 FOUR KNU Creative BioResearch Group, College of Natural Sciences, Kyungpook National University, Daegu 41566, Korea.ORCID https://orcid.org/0009-0007-2141-0147
Hyun-Shik LeeKNU G-LAMP Project Group, KNU Institute of Basic Sciences, School of Biotechnology, BK21 FOUR KNU Creative BioResearch Group, College of Natural Sciences, Kyungpook National University, Daegu 41566, Korea.ORCID https://orcid.org/0000-0002-3837-9867

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isocitrate dehydrogenases (IDHs) catalyze the oxidative decarboxylation of isocitrate to α-ketoglutarate (α-KG), generating NADPH to maintain cellular redox balance. Among the three isoforms, cytosolic Idh1 and mitochondrial Idh2 are NADP

Indexed as

Idh1Idh2Isocitrate dehydrogenasesKidney developmentNephrogenesis

Identifiers

PMID41987874
PMCPMC13077505

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.