ArticleThe open respiratory medicine journal2026
Ventilation-perfusion Scan: A Functional Imaging Approach to Regional Lung Disease in Primary Ciliary Dyskinesia.
Article in The open respiratory medicine journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: As a rare genetic disorder defined by defective ciliary motility, Primary Ciliary Dyskinesia (PCD) leads to chronic respiratory complications. A founder variant in the Methods: Retrospective evaluation of pulmonary function tests, chest imaging, and Tc-99m DTPA ventilation and Tc-99m MAA perfusion scans in ten patients with genetically confirmed Results: Regional lung dysfunction was present in V/Q scans of patients with PCD. Age-related FEV Discussion: These findings suggest that V/Q scans can provide additional functional and physiological information beyond that obtained from CT scans in patients with PCD. Furthermore, future longitudinal studies are needed to confirm their value for monitoring disease progression and guiding clinical care in PCD. Conclusion: V/Q scans may identify functional abnormalities in PCD and complement standard imaging and pulmonary function tests. These scans may serve as valuable tools for monitoring disease progression and informing clinical decision-making.
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