Evidence map›Paper›PMID 41987828›Full record

ArticleISME communications2026

Standing on the shoulders of microbes: microbiome thermal priming buffers the effects of heatwaves on clams by preventing stress overreaction.

Maria Elena Martino, Marialaura Gallo, Ilaria Nai, Andrea Quagliariello, Giulia Dalla Rovere, Massimiliano Babbucci, Giovanna Monticelli, Marco Graziano, Rafaella Franch, Mbarsid Racaku and 4 more

Abstract read
In one paragraph

Article in ISME communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Maria Elena MartinoDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020, Legnaro (PD), Padua, Italy.ORCID https://orcid.org/0000-0001-5038-5605
Marialaura GalloDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020, Legnaro (PD), Padua, Italy.
Ilaria NaiDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020, Legnaro (PD), Padua, Italy.
Andrea QuagliarielloDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020, Legnaro (PD), Padua, Italy.
Giulia Dalla RovereDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020, Legnaro (PD), Padua, Italy.
Massimiliano BabbucciDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020, Legnaro (PD), Padua, Italy.ORCID https://orcid.org/0000-0002-4060-4728
Giovanna MonticelliDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020, Legnaro (PD), Padua, Italy.
Marco GrazianoDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020, Legnaro (PD), Padua, Italy.
Rafaella FranchDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020, Legnaro (PD), Padua, Italy.
Mbarsid RacakuDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020, Legnaro (PD), Padua, Italy.
Barbara CardazzoDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020, Legnaro (PD), Padua, Italy.
Massimo MilanDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020, Legnaro (PD), Padua, Italy.
Luca PeruzzaDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020, Legnaro (PD), Padua, Italy.
Luca BargelloniDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020, Legnaro (PD), Padua, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the context of rapidly accelerating global warming, the rising frequency of heatwaves is driving large-scale ecological shifts, profoundly affecting organismal physiology and ecosystem functioning. Thermal tolerance is a key determinant of species resilience. Evidence from diverse model systems indicates that this tolerance can be enhanced through thermal priming, a pre-adaptive process in which organisms are exposed to sublethal heat stress. Beyond intrinsic host factors, the adaptive potential of host-associated microbiomes is increasingly recognised as a critical role in shaping organismal thermal resilience. However, the extent to which microbiomes alone can enhance host thermal tolerance remains largely unknown. Here, we used the Manila clam (

Indexed as

bivalvesheat waveshost–microbe interactionsmicrobiomethermal primingthermal stress

Identifiers

PMID41987828
PMCPMC13077298

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.